“…Previous epidemiologic studies also reported that greater adherence to a Mediterranean diet rich in vegetables, legumes, cereals, fish, and fruits [9], and healthy eating patterns including vegetables, fruit, whole grains, nuts, and legumes [11] were positively associated with hippocampal volumes in Western subjects, and a diet rich in roasted meat, sausages, hamburgers, and soft drinks was negatively associated with hippocampal volumes in Western subjects. We could not examine the association between brain atrophy and the traditional Mediterranean Diet Score based on daily consumption of seasonal fruit and vegetables, olive oil, cheese, fish, eggs, nuts, wine, and some chicken [28], as Japanese individuals consume less olive oil, cheese, nuts, and wine, which are the main components of the Mediterranean diet. Most previous results regarding the positive association of diets rich in vegetables, fruits, and legumes with hippocampal volume were similar to the findings of our study, but dietary patterns were different.…”