The Medicinal Value and the Numerous Sources of Vitamin C - A Review

Jain, H. K.

doi:10.15406/jnhfe.2015.02.00061

Cited by 3 publications

(2 citation statements)

References 83 publications

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“…Gentisic acid is an important phenolic acid with beneficial therapeutic effects were presented as anti-inflammatory, antimicrobial, hepatoprotective, antigenotoxic, and neuroprotective, remarkably antioxidant activities in in vivo and in vitro studies (Abedi et al, 2020). Abbreviated list of medicinal values of ascorbic acid was reported to prevent from cancer, cardiac diseases, lead toxicity, ocular tissue diseases, and gout; treatment of cancer, diabetes, cognitive impairment, pulmonary function, and common cold (Jain, 2015). Catechin is a phytochemical compound known for its effectiveness as antiinflammatory, antioxidant, anti-cancer, hepatoprotective, anti-diabetic, bactericidal, memory enhancer, antineuroprotective, and anti-arthritis (Baranwal et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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The study aims to investigate the phytochemical composition, antioxidant potential, and anti-cancer activities of Ginkgo biloba L. leaf methanol extract. In this study, the phytochemical compounds, total phenolic and flavonoid contents of G. biloba leaf methanol extract were investigated. Additionally, antioxidant and anti-cancer activities [against HT-29 (human colon cancer line), HeLa (human cervical cancer line), and HEK-293 (human embryonic kidney cell line)] were assayed. The main phytochemical compounds were identified as gallic (0.94±0.01 mg/g), p-hydroxy benzoic (0.71±0.01 mg/g), and protocatechuic (0.60±0.02 mg/g) acids in G. biloba leaf methanol extract by HPLC. The total phenolic and total flavonoid contents were measured as 71.20±0.42 µg GAE/mg extract and 13.24±0.35 µg QE/mg extract, respectively. The high antioxidant activity was found in ABTS•+ assay (89.04±0.71%) while moderate antioxidant activity was observed in DPPH• (43.31±0.75%), metal chelating (49.04±0.49%), CUPRAC (absorbance: 0.85±0.01), and phosphomolybdenum (absorbance: 1.16±0.02) assays at 400 µg/mL. The IC50 values of G. biloba leaf methanol extract on HT-29, HeLa, and HEK-293 cell lines were recorded as 406.70±1.55, 84.86±0.98, and >800 µg/mL, respectively. The present study features a new addition to the antioxidant and anti-cancer properties of the therapeutically valuable G. biloba with its phytochemical content.

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Section: Discussionmentioning

confidence: 99%

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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“…Only the interference of potassium metabisulfite in an amperometric laccase-tyrosinase based biosensor was reported [ 116 ]. Since ascorbic acid (vitamin C) can be found in many foodstuffs as a natural metabolite or food additive (E300–E302) [ 135 , 136 ], the preliminary removal of ascorbic acid from the analyzed sample can be considered as a general strategy aimed at enhancing specificity and/or analysis accuracy in laccase, tyrosinase, and laccase-tyrosinase biosensors.…”

Section: Po-based Biosensors For Estimating Tpi In Frssmentioning

confidence: 99%

Biosensors Based on Phenol Oxidases (Laccase, Tyrosinase, and Their Mixture) for Estimating the Total Phenolic Index in Food-Related Samples

Tarasov

Stozhko

Bukharinova

et al. 2023

Life

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Plant phenolic compounds demonstrate bioactive properties in vitro and/or in vivo, which creates demand for their precise determination in life sciences and industry. Measuring the concentration of individual phenolic compounds is a complex task, since approximately 9000 plant phenolic substances have been identified so far. The determination of the total phenolic content (TPC) is less laborious and is used for the qualimetric evaluation of complex multicomponent samples in routine analyses. Biosensors based on phenol oxidases (POs) have been proposed as alternative analytical devices for detecting phenolic compounds; however, their effectiveness in the analysis of food and vegetal matrices has not been addressed in detail. This review describes catalytic properties of laccase and tyrosinase and reports on the enzymatic and bienzymatic sensors based on laccase and tyrosinase for estimating the total phenolic index (TPI) in food-related samples (FRSs). The review presents the classification of biosensors, POs immobilization, the functions of nanomaterials, the biosensing catalytic cycle, interference, validation, and some other aspects related to TPI assessment. Nanomaterials are involved in the processes of immobilization, electron transfer, signal formation, and amplification, and they improve the performance of PO-based biosensors. Possible strategies for reducing interference in PO-based biosensors are discussed, namely the removal of ascorbic acid and the use of highly purified enzymes.

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Tropical Fruits as Natural, Exceptionally Rich, Sources of Bioactive Compounds

Pereira-Netto

2018

International Journal of Fruit Science

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The Medicinal Value and the Numerous Sources of Vitamin C - A Review

Cited by 3 publications

References 83 publications

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

Biosensors Based on Phenol Oxidases (Laccase, Tyrosinase, and Their Mixture) for Estimating the Total Phenolic Index in Food-Related Samples

Tropical Fruits as Natural, Exceptionally Rich, Sources of Bioactive Compounds

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