The McGill Quality of Life Questionnaire-Revised (MQOL-R). Psychometric properties and validation of a Brazilian version on palliative care patients: a cross-sectional study

Abstract

Background To assess the psychometric properties, including internal consistency, construct validity, criterion validity, criterion-group validity, and responsiveness, the Reviewed McGill Quality of Life Questionnaire (MQOL-R), into Brazilian Portuguese-(BrP). Also, to analyze the relationship of the BrP-MQOL-R with the scores on the Karnofsky Performance Scale (KPS) and on the Numerical Pain Scale (NPS 0–10). Methods The BrP-MQOL-R was administered to a sample of 146 adults (men = 78). A team of experts translated the MQOL-R according to international guidelines. Convergent validity and Confirmatory factor analysis (CFA) was performed. Results The BrP-MQOL-R Cronbach’s alpha was 0.85. CFA supported the original four-factor structure, with the following revised model fit-indices: PCLOSE = 0.131, Tucker-Lewis Index (TLI) rho 2 = 0.918, incremental fit index (IFI) delta 2 = 0.936. The convergence validity is supported by a significant correlation between BrP-MQOL-R total scores and their subscales with KPS and with the single item related to the quality of life. And by a converse correlation with the pain scores in the NPS (0–10). Receiver operator characteristics (ROC) analysis showed subjects with KPS equal to or lower than 30% could be discriminated from those with scores on KPS higher than 30% by an area under the curve (AUC) = 0.71, sensitivity = 97%, and specificity = 92%). Conclusion The BrP-MQOL-R proves to be a reliable instrument for assessing the quality of life (QOL) in palliative care (PC), with primary evidence of validity. BrP-MQOL-R presented adequate discriminate properties to identify distinct conditions that impact the QOL in PC.

The Italian McGill Quality of Life Questionnaire-Revised (MQoL-R): Psychometrics in Neurological and Neoplastic Populations

“…As to the psychometric goodness of the MQoL-R in terms of factorial structure and internal consistency, Italian data herewith delivered aligns with both the original study, 2 within which the English and French versions of the MQoL-R were developed, as well as with the subsequent Polish 3 and Brazilian 4 standardizations – which addressed either neoplastic populations only 3 or both neoplastic and general palliative care patients. 2,4 Therefore, when compared to such studies, 2‐4 the present one provides, for the first time, psychometric evidence on the MQoL-R in a neurological population – mostly including ALS patients. In addition, this work outperforms, as to samples size, both the Polish 3 and Brazilian standardizations 4 – which included 140 and 146 patients, respectively.…”

“…2,4 Therefore, when compared to such studies, 2‐4 the present one provides, for the first time, psychometric evidence on the MQoL-R in a neurological population – mostly including ALS patients. In addition, this work outperforms, as to samples size, both the Polish 3 and Brazilian standardizations 4 – which included 140 and 146 patients, respectively.…”

“…This measure was included for testing the construct validity of the MQoL-R, in accordance with a previous standardization study in a Brazilian neoplastic sample. 4…”

“…Slight, albeit highly effective, changes have been recently introduced through its Revised version (MQoL-R), ie, (1) improved item wording, (2) a greater cohesion of the Physical subscale, (3) a Support subscale more focused on interpersonal relationships (hence renamed “Social”) and (4) Existential subscale retaining only highly performing items. 2 As for its original version, 1 the MQoL-R showed optimal psychometrics and comparability to the MQoL, 2 having been also successfully adapted to Polish 3 and Brazilian 4 samples of in-/out-patients with cancer and/or undergoing palliative care.…”

The Oxygen–Ozone Adjunct Medical Treatment According to the Protocols from the Italian Scientific Society of Oxygen–Ozone Therapy: How Ozone Applications in the Blood Can Influence Clinical Therapy Success via the Modulation of Cell Biology and Immunity

“…Each patient was evaluated for the antimicrobial sensitivity/resistance by MIC assay (see also Table 1). To evaluate patients' QoL following our ozone therapy protocols, an updated form of the McGill QoL questionnaire was used [73][74][75] with patients before accessing the O 2 -O 3 -MAHT and at the end of the therapy cycle (within one week later). The questionnaire evaluated three parameters, from the minimum to the maximum, namely: the Pain Rating Index (PRI), including a scale from 0 to 78; the Pain Rating Index referring to Time (PRIT), with a scoring from 0 to 20; and the Present Pain Intensity (PPI), with a scoring scale of 0-5.…”