The Marigliano–Cacciafesta polypathological scale: A tool for assessing fragility

Amici, A.; Baratta, A.; Linguanti, A.; Giudice, Giuseppe Del; Servello, Adriana; Scalise, Carly Bess; Tafaro, Laura; Cicconetti, P.; Marigliano, Vincenzo; Cacciafesta, Mauro

doi:10.1016/j.archger.2007.05.007

Cited by 22 publications

(30 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Eleven of the 27 instruments included only subjective components which were either reported by a participant (self-evaluation) in nine out of 11 cases [30-34,36,38-40], or reported by a clinician or a researcher (hetero-evaluation) [35,37]. Of the 27 frailty instruments, five included only objective components [41-45].…”

Section: Resultsmentioning

confidence: 99%

“…Of the 27 frailty assessments, 19 were developed in population-based samples [30-32,34-37,40-44,46-48,50,51,53,55], 7 among hospitalized patients [33,39,45,49,52,54,56], and 1 without specification [38]. Half of the frailty scales (n=14) were created by research groups in the USA [30, 31,36,39,41-44,46-49,53,56], five in Canada [32,34,37,52,54], three in the Netherlands [33,40,51], two in Italy [38,45], and one each in Australia [55], France [50], and Sweden [35].…”

Section: Resultsmentioning

confidence: 99%

“…Half of the frailty scales (n=14) were created by research groups in the USA [30, 31,36,39,41-44,46-49,53,56], five in Canada [32,34,37,52,54], three in the Netherlands [33,40,51], two in Italy [38,45], and one each in Australia [55], France [50], and Sweden [35]. Five of the 27 frailty instruments were adapted from those developed initially to assess functional status [57], vulnerability [58], or physical performances [59-61].…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Measures of frailty in population-based studies: an overview

et al. 2013

View full text Add to dashboard Cite

BackgroundAlthough research productivity in the field of frailty has risen exponentially in recent years, there remains a lack of consensus regarding the measurement of this syndrome. This overview offers three services: first, we provide a comprehensive catalogue of current frailty measures; second, we evaluate their reliability and validity; third, we report on their popularity of use.MethodsIn order to identify relevant publications, we searched MEDLINE (from its inception in 1948 to May 2011); scrutinized the reference sections of the retrieved articles; and consulted our own files. An indicator of the frequency of use of each frailty instrument was based on the number of times it had been utilized by investigators other than the originators.ResultsOf the initially retrieved 2,166 papers, 27 original articles described separate frailty scales. The number (range: 1 to 38) and type of items (range of domains: physical functioning, disability, disease, sensory impairment, cognition, nutrition, mood, and social support) included in the frailty instruments varied widely. Reliability and validity had been examined in only 26% (7/27) of the instruments. The predictive validity of these scales for mortality varied: for instance, hazard ratios/odds ratios (95% confidence interval) for mortality risk for frail relative to non-frail people ranged from 1.21 (0.78; 1.87) to 6.03 (3.00; 12.08) for the Phenotype of Frailty and 1.57 (1.41; 1.74) to 10.53 (7.06; 15.70) for the Frailty Index. Among the 150 papers which we found to have used at least one of the 27 frailty instruments, 69% (n = 104) reported on the Phenotype of Frailty, 12% (n = 18) on the Frailty Index, and 19% (n = 28) on one of the remaining 25 instruments.ConclusionsAlthough there are numerous frailty scales currently in use, reliability and validity have rarely been examined. The most evaluated and frequently used measure is the Phenotype of Frailty.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Measures of frailty in population-based studies: an overview

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Medical care of PP must focus on improving the quality of life. The Marigliano-Cacciafesta polypathological scale includes 11 categories of disorders, and has been used to identify frailty in patients [5,6]. To administer the most suitable treatment to each PP, a prognostic stratification is needed.…”

Section: Introductionmentioning

confidence: 99%

External validation of the PROFUND index in polypathological patients from internal medicine and acute geriatrics departments in Aragón

et al. 2015

View full text Add to dashboard Cite

The objective of the study was to validate externally and prospectively the PROFUND index to predict survival of polypathological patients after a year. An observational, prospective and multicenter study was performed. Polypathological patients admitted to an internal medicine or geriatrics department and attended by investigators consecutively between March 1 and June 30, 2011 were included. Data concerning age, gender, comorbidity, Barthel and Lawton-Brody indexes, Pfeiffer questionnaire, socio-familial Gijon scale, delirium, number of drugs and number of admissions during the previous year were gathered for each patient. The PROFUND index was calculated. The follow-up lasted 1 year. A Cox proportional regression model was calculated, and was used to analyze the association of the variables to mortality and C-statistic. 465 polypathological patients, 333 from internal medicine and 132 from geriatrics, were included. One-year mortality is associated with age [hazard ratio (HR) 1.52 95 % CI 1.04-2.12; p = 0.01], presence of neoplasia [HR 2.68 95 % CI 1.71-4.18; p = 0.0001] and dependence for basic activities of daily living [HR 2.34 95 % CI 1.61-3.40; p = 0.0009]. In predicting mortality, the PROFUND index shows good discrimination in patients from internal medicine (C-statistics 0.725 95 % CI 0.670-0.781), but a poor one in those from geriatrics (0.546 95 % CI 0.448-0.644). The PROFUND index is a reliable tool for predicting mortality in internal medicine PP patients.

show abstract

“…Polypathological scale) [4,5,10,11,20,21,[77][78][79]. Most studies indicate a level of frailty for community-dwelling older adults between 5 and 15%.…”

Section: How Prevalent Is Frailty?mentioning

confidence: 99%

Musculoskeletal health, frailty and functional decline

Milte

Crotty

2014

Best Practice & Research Clinical Rheumatology

View full text Add to dashboard Cite

Frailty in older people is associated with a vulnerability to adverse events. While ageing is associated with a loss of physiological reserves identifying those with the syndrome of frailty has the potential to assist clinicians tailor treatments to those at risk of future decline into disability with increased risk of complications, morbidity and mortality. Sarcopenia is a key component of the frailty syndrome and on its own puts older people at risk of fragility fractures however the clinical syndrome of frailty affects musculoskeletal and non musculoskeletal systems. Hip fractures are becoming a prototype condition in the study of frailty. Following a hip fracture many of the interventions are focused on limiting mobility disability and restoring independence with activities of daily living but there are multiple factors to be addressed including osteoporosis, sarcopenia, delirium, weight loss. Established techniques of geriatric evaluation and management allow systematic assessment and intervention on multiple components by multidisciplinary teams and deliver the best outcomes. Using the concept of frailty to identify older people with musculoskeletal problems as at risk of a poor outcome assists in treatment planning and is likely to become more important as effective pharmacological treatments for sarcopenia emerge. This review will focus on the concept of frailty and its relationship with functional decline, as well as describing its causes, prevalence, risk factors and potential clinical applications and treatment strategies. Key wordsFragility fracture, frailty, functional decline, screening, older adult, exercise therapy, dietary therapy Word count 9,401 words (word limit=9,400)

show abstract

The Marigliano–Cacciafesta polypathological scale: A tool for assessing fragility

Cited by 22 publications

References 17 publications

Measures of frailty in population-based studies: an overview

Measures of frailty in population-based studies: an overview

External validation of the PROFUND index in polypathological patients from internal medicine and acute geriatrics departments in Aragón

Musculoskeletal health, frailty and functional decline

Contact Info

Product

Resources

About