The Manitoba Project: a re-examination of the link between menopause and depression

Kaufert, Patricia A.; Gilbert, Penny; Tate, Robert B.

doi:10.1016/0378-5122(92)90006-p

Cited by 289 publications

(158 citation statements)

References 12 publications

Supporting

Mentioning

131

Contrasting

Unclassified

Order By: Relevance

“…This corresponds closely to outcomes obtained earlier in non-childbearing women, using the EDS (27.2%; Cox et al, 1996), and in middle-aged women, using the Center for Epidemiologic Studies Depression Scale (CES-D; Radloff, 1977): 26% (Kaufert et al, 1992). Furthermore, the percentages found are somewhat higher than the percentage of women who were diagnosed as having either minor or major depression, according to the RDC in the present study (21.8%).…”

Section: Discussionsupporting

confidence: 91%

Multiple assessments of depressive symptoms as an index of depression in population-based samples

Nyklı́ček

Scherders

Pop

2004

Psychiatry Research

View full text Add to dashboard Cite

General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.-Users may download and print one copy of any publication from the public portal for the purpose of private study or research -You may not further distribute the material or use it for any profit-making activity or commercial gain -You may freely distribute the URL identifying the publication in the public portal Take down policy If you believe that this document breaches copyright, please contact us providing details, and we will remove access to the work immediately and investigate your claim. AbstractThe incremental validity of repeated measurements of a short depression questionnaire was examined regarding the clinical diagnosis of depression. Participants were 951 randomly selected women of around menopausal age. They completed the Edinburgh Depression Scale (EDS) at two time points, with approximately 18 months in between. At the second time point, they participated in a structured clinical interview for depression diagnosis based on the Research Diagnostic Criteria (RDC). With repeated assessments, specificity and negative predictive value (NPV) did not change much relative to a single assessment, with a specificity of 95.0% and a NPV of 91.7% at a cut-off score of 12 on the EDS. As expected, sensitivity dropped, from 87.9% to 58.8%. However, positive predictive value (PPV) increased from 42.0% to 49.1% at a cut-off of 12. When using a cutoff score of 15 on the EDS, the PPV based on both EDS measurements reached 61.8%, yielding a 25-fold probability of being a case for women scoring above 15 at both time points (OR = 24.54, 95% CI = 14.24 -42.28). In conclusion, the 10-item EDS is a reliable, valid and valuable screening instrument. When employed repeatedly, a more stable depression may be tapped, which can be of substantial value for both epidemiological research and clinical practice.

show abstract

Section: Discussionsupporting

confidence: 91%

Multiple assessments of depressive symptoms as an index of depression in population-based samples

Nyklı́ček

Scherders

Pop

2004

Psychiatry Research

View full text Add to dashboard Cite

show abstract

“…Como seria esperado, as mulheres que referiram sintomas psíquicos atuais, uso atual de antidepressivo e episódio depressivo anterior tiveram pontuação significativamente mais alta. Outros autores já relataram o histórico depressivo pregresso como fator de risco importante para sintomatologia depressiva no climatério [1][2][3][4]9,11,13 .…”

Section: Discussionunclassified

“…Tal achado foi concordante com vários autores que sugeriram que diferentes fatores podem influenciar o aparecimento de sintomas depressivos climatéricos, entre eles o histórico depressivo pregresso [1][2][3][4]9,11,13 . Entre autores nacionais, Soares 15 investigou mulheres em clínica especializada de menopausa com o SRQ-20, e encontrou 49,5% de sintomatologia depressiva significativa.…”

Section: Discussionunclassified

“…As altas taxas de sintomas depressivos obtidas em pesquisas realizadas em clínicas especializadas em menopausa ou em saúde mental [8][9][10][11] não se confirmaram em alguns estudos de base comunitária. Sugeriu-se que a perimenopausa pode ser período de maior risco para os distúrbios do humor, mas não necessariamente representa um momento de risco para a depressão maior 12,13 .…”

Section: Introductionunclassified

See 1 more Smart Citation

Avaliação da sintomatologia depressiva de mulheres no climatério com a escala de rastreamento populacional para depressão CES-D

Fernandes

Rozenthal

2008

Rev. psiquiatr. Rio Gd. Sul

View full text Add to dashboard Cite

ResumoIntrodução: O objetivo deste estudo foi avaliar a sintomatologia depressiva em mulheres climatéricas com a escala de depressão CES-D (Center for Epidemiological Studies Depression Scale), do National Institute of Mental Health (EUA). Método: Estudo transversal com 151 mulheres entre 40 e 65 anos de idade, usuárias de serviço de ginecologia geral em unidade de atenção básica à saúde no Rio de Janeiro. Aplicou-se a escala CES-D e um questionário estruturado para a obtenção de dados sociodemográficos, clínicos e ginecológicos. O nível de corte > 15 pontos na CES-D foi considerado como indicativo de quadro depressivo. Resultados: A média de pontuação da amostra foi de 9,2 pontos (desvio padrão = 9,0). Os itens mais pontuados da escala foram relativos à insônia, tristeza e desânimo. Não houve associação significativa entre os escores e o período climatérico, características sociodemográficas, clínicas ou ginecológicas, exceto para as mulheres com presença de sintomas psíquicos, histórico depressivo pregresso e uso atual de antidepressivos (p = 0,000). Entre as 32 mulheres (21%) com pontuação > 15 na CES-D, 72% referiram episódio depressivo pregresso. Dentre as participantes sem histórico depressivo, as perimenopáusicas apresentaram escores > 15 com maior freqüência. Conclusão: Essa casuística, oriunda de serviço não-especializado em menopausa ou saúde mental, revelou baixas pontuações médias na escala de sintomas depressivos CES-D, e o item insônia foi o mais pontuado. O histórico de depressão foi fator de associação com a alta pontuação na escala, mas não a fase climatérica em que a mulher se encontrava. A maior freqüência de pontuação acima do nível de corte nas mulheres sem histórico depressivo pregresso que estavam na perimenopausa sugere a maior vulnerabilidade, nessa fase, a episódios depressivos novos. Descritores: Climatério, menopausa, depressão. AbstractIntroduction: The objective of this study was to evaluate depressive symptoms in climacteric women using the Center for Epidemiological Studies Depression Scale (CES-D) from the National Institute of Mental Health (USA). Method: This is a cross-sectional study carried out in a gynecological outpatient unit in Rio de Janeiro, Brazil, including 151 climacteric women between 40 and 65 years of age. The CES-D was used to assess depressive symptoms and a structured interview obtained sociodemographic, clinical and gynecological data. A score above 15 points on the CES-D was considered as a cut-point for depressive state. Results: Mean CES-D score was 9.2 points (standard deviation = 9.0). Insomnia, sadness and despondency had the highest scores. There was no significant association between CES-D scores and the climacteric period, sociodemographic, clinical or gynecological characteristics, except for women with psychiatric symptoms, history of depression or on antidepressants (p = 0.000). In 32 women

show abstract

“…Years δεν βρήκε αυξηµένα ποσοστά άγχους και κατάθλιψης σε γυναίκες κατά τη µετάβασή τους στην εµµηνόπαυση (20), όπως και ο Matthews, o οποίος δεν βρήκε κάποια συσχέτιση µεταξύ κατάθλιψης και περιεµµηνόπαυσης (21). Στο ίδιο συµπέρασµα κατέληξε και η National Health Examination Follow Up Study , η οποία µελέτησε γυναίκες ηλικίας 45-54 ετών (22).…”

Section: παράδειγµα η µελέτη Manitoba Project On Women and Their Healunclassified

Ορμονικοί Και Ανοσολογικοί Δείκτες Καταθλιπτικών Γυναικών Στην Κλιμακτήριο

Καραουλάνης¹

View full text Add to dashboard Cite

The Manitoba Project: a re-examination of the link between menopause and depression

Cited by 289 publications

References 12 publications

Multiple assessments of depressive symptoms as an index of depression in population-based samples

Multiple assessments of depressive symptoms as an index of depression in population-based samples

Avaliação da sintomatologia depressiva de mulheres no climatério com a escala de rastreamento populacional para depressão CES-D

Ορμονικοί Και Ανοσολογικοί Δείκτες Καταθλιπτικών Γυναικών Στην Κλιμακτήριο

Contact Info

Product

Resources

About