The Lundh test in the diagnosis of pancreatic disease: A review of five years' experience

Abstract

SUMMARY An analysis of 523 Lundh tests performed on 492 patients over a five-year period has been made. The results suggest that the test is a simple, cheap, and reliable procedure for the diagnosis of pancreatic exocrine insufficiency, and is suitable for both specialized units and general hospitals. It is particularly useful in the differential diagnosis of patients with steatorrhoea or obstructive jaundice and can often distinguish between malignant and benign lesions, as well as indicating the site of the obstruction. It is of lesser value in the diagnosis of abdominal pain.

The Lundh test and faecal elastase 1 determination in chronic pancreatitis: A comparative study

“…The Lundh test does not involve quantitative aspiration of the duodenal content, and the enzyme concentrations measured represent the digestive hydrolytic milieu in the duodenum, giving a semiquantitative measurement of the exocrine pancreatic function. The test is technically easy to perform and reflects to a greater extent the physiological conditions of the exocrine pancreatic function than the secretin-CCK test [11]. The predictive power of the Lundh test is close to that of the secretin-CCK test [3], but may be lower, especially in patients with only slightly reduced pancreatic function [12], although the opposite has been found [13].…”

A Rapid, Endoscopic Exocrine Pancreatic Function Test and the Lundh Test: A Comparative Study

“…This makes the test useful in the diagnostic workout of early chronic pancreatitis. The Lundh meal test does not measure the pancreatic secretory capacity, but rather pancreas ability to maintain normal concentrations of pancreatic enzymes in the duodenum under physiological conditions [9] . Nevertheless, the sensitivity of the test is close to that of the secretin-CCK test [10] , and the test is well suited for the clinically relevant graduation of patients suspected for chronic pancreatitis: abolished, preserved but reduced, and NEPF.…”

Cimetidine: effect on pancreatic and biliary function in man.

“…Furthennore, no individual subject had a mean two hour tryptic activity below the normal range of 7-38i mol H+ min-' ml-' (Mottaleb, Kapp, Noguera, Kellock, Wiggins & Waller, 1973), nor a jejunal bile acid concentration below that necessary for micellar solubilization of a normal dietary load of fat (4pmol/ml according to Badley, Murphy & Bouchier, 1969).…”