The Los Angeles Classification of Gastroesophageal Reflux Disease

Sami, SS; Ragunath, Krish

doi:10.1016/s2212-0971(13)70046-3

Cited by 69 publications

(46 citation statements)

References 3 publications

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“…She was treated with the 40 mg twice daily PPI (full dose) for the next 7 days followed by 40 mg once a day of PPI (single dose) for the next 21 days and discontinuation of clindamycin therapy was recommended. At the first follow-up visit 1 month later, oesophagogastroduodenoscopy showed the oesophagus was free of strictures, ulcers, erosions and bleeding, but mild GERD (grade A) was present 1. The patient experienced a complete clinical resolution after 3 weeks of PPI treatment.…”

Section: Case Presentationmentioning

confidence: 92%

Clindamycin-induced necrotising oesophagitis

Benić¹,

Karlović

Čubranić

2016

Postgraduate Medical Journal

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Section: Case Presentationmentioning

confidence: 92%

Clindamycin-induced necrotising oesophagitis

Benić¹,

Karlović

Čubranić

2016

Postgraduate Medical Journal

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“…After informing participants of the reason for this research project, the researcher obtained written informed consent from the patient before the interview. Preliminary information, such as a patient's medical diagnosis, age, sex, pulmonary function test results and PES results (using the Los Angeles scale from A–D) (Sami & Ragunath, ), were obtained by researchers through chart review of participants’ medical records.…”

Section: Methodsmentioning

confidence: 99%

“…Preliminary information, such as a patient's medical diagnosis, age, sex, pulmonary function test results and PES results (using the Los Angeles scale from A-D) (Sami & Ragunath, 2013), were obtained by researchers through chart review of participants' medical records.…”

Section: Data Collectionmentioning

confidence: 99%

Acute exacerbations of chronic obstructive pulmonary disease (COPD) experiences among COPD patients with comorbid gastrooesophageal reflux disease

Lin

Tsai

Tsao

et al. 2019

Journal of Clinical Nursing

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Aims and objectives To explore perceptions of experience exacerbations of chronic obstructive pulmonary disease among chronic obstructive pulmonary disease patients with comorbid gastrooesophageal reflux disease by focusing on unravelling how patients differentiate and react to symptoms of chronic obstructive pulmonary disease and gastrooesophageal reflux disease. Background While gastrooesophageal reflux disease has been suggested to be a risk factor for chronic obstructive pulmonary disease exacerbations, no study has explored perceptions of the symptoms leading up to severe exacerbation of chronic obstructive pulmonary disease events among chronic obstructive pulmonary disease patients with comorbid gastrooesophageal reflux disease. Design Qualitative design. Methods The analysis was performed in accordance with principles of Grounded Theory methodology. Data were collected via semi‐structured interviews from 12 chronic obstructive pulmonary disease patients with endoscopy‐diagnosed gastrooesophageal reflux disease who had experienced a chronic obstructive pulmonary disease exacerbation with hospitalisation. Appraisal and analysis using consolidated criteria for reporting qualitative research (COREQ) checklist were undertaken. Results The core category of this study was the ineffective management of exacerbation symptoms, which was associated with perceived symptoms pre‐exacerbation which contained three overlapping categories of symptom presentation experienced, and chronic obstructive pulmonary disease‐related coping strategies, high anxiety and a sense of helplessness in disease management. Conclusions Patients with severe chronic obstructive pulmonary disease with comorbid gastrooesophageal reflux disease presented with some distinctly different atypical symptoms yet used common respiratory symptom management strategies. Patients and practitioners alike need to be more aware of the possibility of other symptoms such as nonspecific symptoms being clues of exacerbation onset for a more effective intervention. Relevance to clinical practice The medical community needs to educate patients to understand and manage not only chronic obstructive pulmonary disease but also gastrooesophageal reflux disease symptoms so that they are better able to identify the cause of their symptoms, treat them appropriately and seek out medical assistance when necessary.

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“…Male or female adult patients (age, 18–65 years; body weight, >60 kg; body mass index [BMI], <35 kg m −2 ) with a ≥3‐month history of moderate‐to‐severe GERD reflux symptoms (as defined by heartburn or acid regurgitation on more than 2 days per week and/or nocturnal reflux and/or postprandial reflux) were enrolled. Each patient was required to have uncomplicated reflux esophagitis (Los Angeles classification A or B) or a pathological esophageal pH (pH <4 for ≥9% of the time over 24 hours) within 24 months prior to enrollment. Concomitant treatment with PPIs was allowed provided dosing had been maintained for at least 4 weeks.…”

Section: Methodsmentioning

confidence: 99%