The long-term follow-up of patients with endoscopically diagnosed reflux oesophagitis with specific emphasis to complaints

Abstract

Despite effective therapy, only 37% of the patients are in complete remission. However, the individual symptom score is rather low. Patients without medication more often have reflux complaints but lower severity scores. Patients who still had complaints and used medication had a hiatal hernia significantly more often.

Long-term follow up in patients with gastroesophageal reflux disease with specific emphasis on reflux symptoms, use of anti-reflux medication and anti-reflux surgery outcome: a retrospective study

“…Daily PPI use was lower in patients who underwent anti-reflux surgery and increased with older age. The findings of this study with regard to frequency and severity of typical reflux complaints and use of PPIs are in agreement with results of previous studies [16][17][18]24]. In a retrospective cohort study, a trend toward chronicity of reflux symptoms with relative low symptom scores was observed.…”

“…It was shown that, despite effective therapy, only 37% of the patients were in complete remission. However, when patients were still symptomatic, the individual symptom scores were actually found to be rather low [16]. In another study, it was found that, after more than 10 years of follow up, 76% of the 101 included patients previously diagnosed with esophagitis during upper endoscopy still had frequent symptoms or took regular antireflux medication [17].…”

Risk Factors for Resistance to Proton Pump Inhibitor Maintenance Therapy for Reflux Esophagitis in Japanese Women over 60 Years

“…These risk factors for older Japanese women were similar to the risk factors demonstrated in previous studies focusing on Japanese patients with reflux esophagitis [8,9,20]. Most previous studies evaluated the effects of PPI on reflux esophagitis by endoscopic examination, pH monitoring and questionnaires [8,9,20,21,22,24,25,26,27,28,29,30,31,32,33]. However, the present study indicates that evaluation of the therapeutic effects of PPI by the physicians who take care of reflux patients in daily clinical situations may be convenient and useful compared with evaluation by endoscopy and/or questionnaires.…”

Long-Term Outcome Of Patients With Functional Dyspepsia Infected With A Cag-Positive Helicobacter Pylori Strain. A Descriptive Study

“…Patients not capable of reading the Dutch language were excluded. The questionnaire was already used and validated in previous studies [13,14]. The questionnaire was composed of four different lists of questions pertaining to upper abdominal complaints.…”

“…A general questionnaire consisted of 20 questions [13,14]. The first question in the general questionnaire was: "Do you experience any upper abdominal complaint?"…”