The literature of heterocyclic chemistry, part XVIII, 2018

Беленький, Л. И.; Газиева, Галина А.; Evdokimenkova, Yu. B.; Соболева, Н. О.

doi:10.1016/bs.aihch.2020.01.002

Cited by 14 publications

(2 citation statements)

References 677 publications

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“…Nitrogen- and sulfur-containing heterocycles are found in many natural products and biologically active molecules. 1 This diversity of compounds includes imidazolidin-2-one and hydrogenated thiazole derivatives. For example, biotin (5-[2-oxohexahydro-1 H -thieno[3,4- d ]imidazol-4-yl]pentanoic acid) is involved in a wide range of metabolic processes in living organisms as a cofactor for carboxylase enzymes, 2 and leucogen (2-(2-ethoxy-2-oxo-1-phenylethyl)thiazolidine-4-carboxylic acid) is a veterinary vaccine used to protect cats against feline leukemia virus.…”

Section: Introductionmentioning

confidence: 99%

Dimroth-type N/S-interchange of N-aminothioglycolurils in the synthesis of 2-hydrazonoimidazo[4,5-d]thiazolones

et al. 2021

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Section: Introductionmentioning

confidence: 99%

Dimroth-type N/S-interchange of N-aminothioglycolurils in the synthesis of 2-hydrazonoimidazo[4,5-d]thiazolones

et al. 2021

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“…In addition, ILs have following applications: as reagents and scavengers, to synthesize energy storage materials, to desulfurize fuel, for energy production, for carbon capture, functional material, and in denitrogenating of fuel oils [9]. According to their applications, many kinds of ILs were synthesized till now: acidic ILS, functionalized ILs, covalently and non-covalently supported ILs, ILs transported into metal-organic frame-works (MOFs), superionic liquids, and magnetic ILs, which each of them have their unique properties [10].…”

Section: Introductionmentioning

confidence: 99%

ZnBr2 Functionalized Ionic Liquid: An Efficient Solvent and Catalyst for the Facile Synthesis of 1-Benzamino-1,4-Dihydropyridine

Zand

Leili

Ghafuri

2019

The 23rd International Electronic Conference on Synthetic Organic Chemistry

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Ionic liquids (ILs) are mostly composed of organic cations and organic/inorganic anions. One of the most important class of ILs are imidazolium ILs. The hydrophilicity and hydrophobicity of ILs are regularly influenced by length of alkyl side chain of cation. According to this effect, better hydrophilicity comes from a shorter alkyl side chain and on the contrary, better hydrophobicity comes from a lengthier alkyl side chain of cation. Typical ILs have exceptional properties. Most ILs are stable at about 300 o C in the liquid state at normal conditions. Due to the exceptional properties of ILs, they have been used in diverse industries including batteries and fuels. As solvents, ILs have been employed in many chemical fields. Solubilities of ILs with organic/inorganic species are completely satisfactory. Here, by N-methyl imidazole (Im), 1,3-dibromopropane, triethanolamine (TEA), and ZnBr2, new ionic liquid (TEA-Im-Zn) was synthesized and used as catalyst and solvent in the synthesis of functionalized 1-benzamino-1,4-dihydropyridine using aromatic aldehydes, malononitrile, triethylamine, arylamine and dialkyl acetylenedicarboxylate.

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Ring Distortion Diversity‐Oriented Approach to Fully Substituted Furoxans and Isoxazoles

2021

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A regioselective method for an assembly of pharmacologically relevant fully substituted furoxans and isoxazoles using the ring distortion diversity‐oriented approach through the one‐pot ring cleavage/nucleophilic addition/oxidation cascade of monosubstituted furoxans was developed. The described synthetic strategy is highly regioselective and provides single furoxan regioisomers upon utilization of N‐ or S‐nucleophiles. Utilization of the cyanide‐anion as a nucleophile in the same reaction cascade afforded a series of rather rare fully substituted isoxazoles incorporating vicinal nitro and amino functionalities. In addition, synthesized disubstituted furoxans revealed an ability to release NO indicating their strong potential as pharmacologically oriented drug candidates for various biomedical applications.

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The literature of heterocyclic chemistry, part XVIII, 2018

Cited by 14 publications

References 677 publications

Dimroth-type N/S-interchange of N-aminothioglycolurils in the synthesis of 2-hydrazonoimidazo[4,5-d]thiazolones

Dimroth-type N/S-interchange of N-aminothioglycolurils in the synthesis of 2-hydrazonoimidazo[4,5-d]thiazolones

ZnBr2 Functionalized Ionic Liquid: An Efficient Solvent and Catalyst for the Facile Synthesis of 1-Benzamino-1,4-Dihydropyridine

Ring Distortion Diversity‐Oriented Approach to Fully Substituted Furoxans and Isoxazoles

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