The light-addressable potentiometric sensor for multi-ion sensing and imaging

Yoshinobu, Tatsuo; Iwasaki, Hiroshi; Y, Ui; Furuichi, K.; Ermolenko, Yu. Е.; Mourzina, Yulia; Wagner, Torsten; Näther, Niko; Schöning, Michael J.

doi:10.1016/j.ymeth.2005.05.020

Cited by 141 publications

(67 citation statements)

References 47 publications

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“…LAPS has been used successfully for the electrochemical imaging of specific ions, DNA detection, monitoring of enzymatic reactions, microorganisms, activities and extracellular potentials of cells [10][11][12][13][14][15][16] with a typical resolution of about 10-100 µm using LED arrays as the light source. Using an optimized laser scanning setup in conjunction with a silicon-onsapphire (SOS) substrate (Figure 1), 1.5 µm spatial resolution was obtained using visible light with a wavelength of 405 nm, and 0.8 µm resolution was achieved using light with energy smaller than the bandgap exciting a two-photon effect in silicon [17,18].…”

Section: Introductionmentioning

confidence: 99%

Image detection of yeast Saccharomyces cerevisiae by light-addressable potentiometric sensors (LAPS)

Zhang

Wang

et al. 2016

Electrochemistry Communications

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Section: Introductionmentioning

confidence: 99%

Image detection of yeast Saccharomyces cerevisiae by light-addressable potentiometric sensors (LAPS)

Zhang

Wang

et al. 2016

Electrochemistry Communications

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“…(71)(72)(73) A laminar flow in a Y-shaped channel and ion diffusion across the boundary were visualized to determine the diffusion coefficient. (73) Figure 4 shows photocurrent distributions inside the Y-shaped channel, in which ion diffusion between different flow rates of laminar flows were observed.…”

Section: Ion Diffusionmentioning

confidence: 99%

Development and Bio-imaging Applications of a Chemical Imaging Sensor

2016

Sensors and Materials

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A chemical imaging sensor is a field-effect-based semiconductor sensor, capable of label-free imaging of ion distributions in a solution. The sensor has attracted much interest owing to its simple structure and diverse fields of application of bioimaging. In this article, the principle and development of the chemical imaging sensor are summarized, compared with those of other labelfree imaging sensors. Bio-imaging applications of the chemical imaging sensor to ion diffusion, enzymatic reaction, and metabolic activities of microorganisms are also reviewed.

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“…Research groups worldwide have made attempts to improve the LAPS based sensors system technology [34][35][36][37]. The Cytosensor was used in the analysis of membrane bound receptors [38] and non-receptor mediated events on cell metabolism like the detection of heavy metals [39].…”

Section: Molecular Devices Cytosensor Microphysiometermentioning

confidence: 99%

A critical comparison of cell-based sensor systems for the detection of Cr(VI) in aquatic environment

Bohrn

Mucha

Werner

et al. 2013

Sensors and Actuators B: Chemical

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a b s t r a c tThe toxicity of chromium ions was investigated using mammalian cell cultures on impedance sensors as well as physiological in vitro sensor systems. The performance of commercially available systems like the 2500 Analyzing System (Bionas), xCELLigence (Roche) and Cytosensor Microphysiometer (Molecular Devices) was compared with a novel CMOS-based impedance-to-frequency converter device. Cell-based sensor systems are shown to be powerful tools to detect Cr(VI) pollutions within several hours in the range of multinational drinking water regulations. The ability to distinguish between toxic Cr(VI) and non-toxic Cr(III) species is one advantage of these integral sensor systems. Impedance only devices are not sufficient for the fast detection of toxic chromium species as rapid cellular changes occur only in the respiration system and the cell physiology.

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The light-addressable potentiometric sensor for multi-ion sensing and imaging

Cited by 141 publications

References 47 publications

Image detection of yeast Saccharomyces cerevisiae by light-addressable potentiometric sensors (LAPS)

Image detection of yeast Saccharomyces cerevisiae by light-addressable potentiometric sensors (LAPS)

Development and Bio-imaging Applications of a Chemical Imaging Sensor

A critical comparison of cell-based sensor systems for the detection of Cr(VI) in aquatic environment

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