The lesions of fifteen hundred placentas considered from a clinical point of view

The Significance of Placental Infarction in Perinatal Morbidity and Mortality

“…This is exemplified by the confusion surrounding the relationship between pre-eclamptic toxaemia and infarction of the placenta, about which three conflicting schools of thought have arisen (Table I). The first maintains that 'acute' infarcts of the placenta are pathognomonic of toxaemia and are, furthermore, the cause of the toxaemic symptoms [3,4,5,32,53,63], whilst the second has thought that infaredon is the result rather than the cause of the toxaemic process [1,6,14,16,18,20,25,26,27,30,34,35,36,37,40,43,44,45,47,49,51,52,55,56,57,59,60,61,64,65] and that, although die incidence of placental in farction is significantly increased in toxaemia, the presence of infarcts is not an invariable feature. By contrast, a third group of workers have been unable to confirm that the incidence of placental infarction in cases of pre-eclamptic toxaemia is notably different from that found in uncomplicated pregnancies [15,17,28,39,41,46,…”

Placental Chorioangioma: A Case Report and Literature Review

“…Chorioangiomas are the commonest benign tumours of the placenta, with an incidence of 1% with systemic examination of the placenta picking up small tumours 1 . With large tumours, however, the incidence varies from one in 500 to one in 16,000 placentas, 2,4 and large tumours with diameters greater than 5 cm may be associated with maternal and fetal complications, including polyhydramnios, arteriovenous shunt mechanisms leading to fetal anaemia, cardiac hypertrophy and failure, intrauterine death, pre‐term labour, low birth weight, pre‐eclampsia and congenital malformation 1,5‐8 …”

Human Decidual Spiral Arterial Studies

“…James Young (19 14, I927), Colvin (1939, Falkiner (1942), Javert and Reiss (1952), Assali (1950, 1952) and others have commented on its higher incidence in toxaemia, the round shape and its pathogenesis. Traut and Kuder (1934), after a study of 1,500 fresh placentae, deny that a higher incidence exists in the toxaemic group, though they found a higher incidence of large infarcts with damage to the infant in this group. has been unable to demonstrate any precise correlation between the amount and location of infarction and the clinical manifestations of toxaemia.…”