The Left Ventriculogram in Experimental Myocardial Infarction

Pc, Pairolero; Fj, Hallermann; Fh, Ellis

doi:10.1148/95.2.311

Cited by 20 publications

(2 citation statements)

References 7 publications

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“…Pairolero et al (1970) made serial estimations of left ventricular ejection fraction in the conscious dog after ligation of a coronary artery, and reported that the ejection fraction fell after ligation but rose to a steady level one month later. Karsner and Dwyer (1916) in canine studies reported that replacement of the infarcted myocardium by scar tissue was not established until 16 days after ligation of the coronary artery, while complete scar formation had not occurred until 61 days after the ligation.…”

Section: Ventricular Functionmentioning

confidence: 99%

Correlation of ejection fraction and infarct size estimated from the total CK released in patients with acute myocardial infarction.

Hori¹,

Inoue²,

Fukui³

et al. 1979

Heart

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SUMMARY In order to investigate the relation between infarct size in acute myocardial infarction and left ventricular ejection fraction early after recovery, total creatine kinase released was calculated by the modified method of Sobel et al. (1972) from the serial determinations of serum CK activity; left ventriculography and selective coronary arteriography were performed at a mean of 2 months after the onset of infarction in 34 patients with acute myocardial infarction. Of 34 patients, 32 (94%) had left ventricular asynergy. In 21 patients with akinesis and/or dyskinesis, a significant correlation was found between the extent of thenon-contractingsegmentof theleft ventricle and left ventricular ejection fraction, indicating that the extent of the non-contracting segment contributes largely to reduction of ejection fraction in patients with myocardial infarction.A close inverse correlationwas also observed between theinfarct size and ejection fraction after anterior and after inferior infarction, though cardiac index was maintained over 2-0 1/min per m2 in all except 3 patients. The ejection fraction in patients with anterior myocardial infarction was lower than in those patients with inferior myocardial infarction with comparable values of total CK released. This was true even after exclusion of 6 patients with proximal right coronary artery lesions who might have had right ventricular necrosis as well as left, indicating that left ventricular function after infarction depends in part on the site of the infarct.Since Harrison (1965) In the present study, we attempted to estimate infarct size by calculating the total CK released from infarcted myocardium using the method of Sobel et al. (1972)

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Section: Ventricular Functionmentioning

confidence: 99%

Correlation of ejection fraction and infarct size estimated from the total CK released in patients with acute myocardial infarction.

Hori¹,

Inoue²,

Fukui³

et al. 1979

Heart

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“…A quantitative relation between the size of an akinetic segment and ejection fraction has been described in the experimental animal (Pairolero et al, 1970) and in man (Feild et al, 1972;Rigo et al, 1974) but no study has compared results from different projections.…”

Section: Discussionmentioning

confidence: 99%

Comparison of single plane and biplane radionuclide ventriculograms performed in oblique projections in patients with acute myocardial infarction.

Dymond¹,

Stone²,

Elliott³

et al. 1979

Heart

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summARY Thirty-five patients were studied by first pass radionuclide ventriculography in both right anterior oblique and left anterior oblique projections, after an acute myocardial infarction. Left ventricular ejection fraction was measured in both obliques from the background corrected time-activity curves and the values correlated closely. Mean left ventricular ejection fraction from the two obliques correlated well with that measured from the ventricular perimeters using a biplane area-length formula. End-diastolic volume from the single plane right anterior oblique correlated with that measured using the biplane formula. Combined right and left anterior oblique projections allowed identification of akinetic sites in all patients, whereas the right anterior oblique alone failed to delineate akinetic sites in 1/10 (10%) of patients with anterior infarction, 2/9 (22%) with inferior infarction, and 6/16 (37%) with multiple areas ofinfarction. The

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