“…Notwithstanding, other UCLP occlusion studies with either passive PSIO and sequential primary bone grafting (Hathaway et al, 1999) or active Latham PSIO without primary alveolar surgery (Chan et al, 2003) showed both protocols achieved dental arch relationships in preadolescence like children without PSIO intervention nor alveolar grafting. Finally, active Latham PSIO treatment categorically shifts the native growth-compensated developmental derangement while normalizing cleft component positions (Spolyar et al, 1992). In a UCLP cast study, larger cleft width (derangement) in infancy between cuspid points was significantly associated with less anterior and posterior dental crossbite at age 5 years (Reiser et al, 2010); would that the native growth-compensated developmental derangement having been normalized by PSIO, then lead to more crossbites?…”