The investigation on the skin whitening efficacy of Chinese herb extracts using the colour physics technology

Shu, Yi-Ting; Weng, Ching-Sung; Kuo, Wen-Guey; Jiang, George J.; Kao, Kuo-Ting

doi:10.1016/j.jdermsci.2004.10.005

Cited by 5 publications

(2 citation statements)

References 3 publications

(3 reference statements)

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“…Wolf), and Tribuli Fructus (dried ripe fruit of Tribulus terrestris L.) [8]. Recent scientific studies also supported the notion that the different herbs within QBS are potent on reducing the skin colour of healthy volunteers receiving recreational exposure to sunlight [9]. Laboratory experiments demonstrated that these herbs from QBS could significantly inhibit tyrosinase activity, thereby contributing to their effects in the control of pigmentations [7].…”

Section: Introductionmentioning

confidence: 99%

In Search of an Innovative Agent for Skin Care - Putting an Ancient Herbal Cosmetic Formula on Modern Bioactivity Testing Platforms

2019

J Clin Investig Dermatol

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Inviting Innovations in wrinkles, sagginess, pigmentation or even neoplastic changes [4]. While these undesirable effects could be minimised with avoidance of strong sunlight and harmful exposures, topical applications of various types of agents have been very common practices The usage of topical agents, also known as cosmetics for the management of skin conditions and improvement of its outlook is a common practice among different cultures. The word "cosmetics" arises from the Greek "kosmeticos" meaning "adorn". Since then, any material used for beautification or improvement of appearance is known as cosmetics [5]. This need for adorning the appearance and conditions of the face has been an urge in the human race of different regions and cultures since ancient times, leading to the invention of different remedies which were handed down for generations with unabated enthusiasm.Herbal medicines have been used as skin-whitening agents since ancient times [6,7]."Qi Bai San (QBS)" is one of such ancient herbal cosmetic classic especially used by Royal Family members and dignitaries as topical agent [7]. According to Yong Lei Qian Fang written by Zhong Nan Li, a famous Chinese medicine practitioner during the Yuen Dynasty, QBS was traditionally used for the treatment of skin pigmentations and consisted of seven different Chinese herbs [8]. This formula may vary slightly but contain herbs of which all in Chinese language carry the word "White", signifying its whitening effects. These herbs include Ampelopsis Radix (dried root tuber of Ampelopsis japonica (Thunb.) Makino), Atractylodis Macrocephalae Rhizoma (dried rhizome of Atractylodes macrocephala Koidz.),

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Section: Introductionmentioning

confidence: 99%

In Search of an Innovative Agent for Skin Care - Putting an Ancient Herbal Cosmetic Formula on Modern Bioactivity Testing Platforms

2019

J Clin Investig Dermatol

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“…In addition to dermatological research, many other fields have shown increased interest in identifying agents from natural resources, including cosmetics, functional foods, beverages, and feed additives in livestock [6–9]. In the cosmetic field, many studies have attempted to identify medicinal herbs and traditional medicines that can inhibit melanin and tyrosinase activity, which could be used as skin-whitening agent [10]. Many types of natural resources and products including various plants (whole plant or part) and extracts of various solvents have been screened with this goal in mind [11, 12].…”

Section: Introductionmentioning

confidence: 99%

Inhibitory Effect of Arctigenin from Fructus Arctii Extract on Melanin Synthesis via Repression of Tyrosinase Expression

Park

Song²,

Jung³

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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To identify the active compound arctigenin in Fructus Arctii (dried seed of medicinal plant Arctium lappa) and to elucidate the inhibitory mechanism in melanogenesis, we analyzed melanin content and tyrosinase activity on B16BL6 murine melanoma and melan-A cell cultures. Water extracts of Fructus Arctii were shown to inhibit tyrosinase activity in vitro and melanin content in α-melanocyte stimulating hormone-stimulated cells to similar levels as the well-known kojic acid and arbutin, respectively. The active compound arctigenin of Fructus Arctii displayed little or no cytotoxicity at all concentrations examined and decreased the relative melanin content and tyrosinase activity in a dose-dependent manner. Melanogenic inhibitory activity was also identified in vivo with zebrafish embryo. To determine the mechanism of inhibition, the effects of arctigenin on tyrosinase gene expression and tyrosinase promoter activity were examined. Also in addition, in the signaling cascade, arctigenin dose dependently decreased the cAMP level and promoted the phosphorylation of extracellular signal-regulated kinase. This result suggests that arctigenin downregulates cAMP and the tyrosinase enzyme through its gene promoter and subsequently upregulates extracellular signal-regulated kinase activity by increasing phosphorylation in the melanogenesis signaling pathway, which leads to a lower melanin content.

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Analysis of active compounds and geographical origin discrimination of Atractylodes macrocephala Koidz. by using high performance liquid chromatography-diode array detection fingerprints combined with chemometrics

Tong

Wang

Chang

et al. 2022

Journal of Chromatography A

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The investigation on the skin whitening efficacy of Chinese herb extracts using the colour physics technology

Cited by 5 publications

References 3 publications

In Search of an Innovative Agent for Skin Care - Putting an Ancient Herbal Cosmetic Formula on Modern Bioactivity Testing Platforms

In Search of an Innovative Agent for Skin Care - Putting an Ancient Herbal Cosmetic Formula on Modern Bioactivity Testing Platforms

Inhibitory Effect of Arctigenin from Fructus Arctii Extract on Melanin Synthesis via Repression of Tyrosinase Expression

Analysis of active compounds and geographical origin discrimination of Atractylodes macrocephala Koidz. by using high performance liquid chromatography-diode array detection fingerprints combined with chemometrics

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