The Investigation of Demographic Characteristics and the Health-Related Quality of Life in Patients With Diabetic Foot Ulcers at First Presentation

Huang, Yao; Xie, Ting; Wu, Minjie; Cao, Yemin; Wang, Xiqiao; Jiang, Yuzhi; Tian, Ming; Wu, Weida; Peifen, Qian; Lu, Shuliang

doi:10.1177/1534734612457034

Cited by 22 publications

(34 citation statements)

References 19 publications

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“…This has a great influence in the development of diabetic foot ulcers because the patients do not fully understand both the importance of taking care of the feet and the severity of having T2DM [20–22]. This is consistent with other studies [23–26]. In fact, recent studies have shown that people with a higher level of education are more aware of the severity of having T2DM, take better care of their condition, and participate more in programs devoted to the care of the diabetic foot and the prevention of foot ulcers [27,28].…”

Section: Discussionsupporting

confidence: 88%

Clinical and surgical characteristics of infected diabetic foot ulcers in a tertiary hospital of Mexico

Cervantes-García

Salazar-Schettino

2017

Diabetic Foot & Ankle

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Background: The objective of this study was to determine the clinical and surgical characteristics of diabetic foot ulcers in a tertiary level hospital in Mexico. Methods: We performed a longitudinal, descriptive study from July, 2012 to August, 2015 on a sample composed of 100 patients with type 2 diabetes mellitus and infected diabetic foot ulcers. We analyzed socio-demographic variables, comorbidities, characteristics of ulcers, and the applied treatment. Results: We found that the most affected areas were the forefoot (48%) and the plantar region (55%) of the foot. Also, most of the patients arrived with advanced stages of diabetic foot ulcers, since 93% of the lesions were of grades III–V according to the Wagner classification. Moreover, lesions usually present with advanced states of infection, since 60% of the lesions were of grades 3–4 in the PEDIS scale. In addition, the great majority of the patients are prone to complications because we found that 43% of the patients suffered from hypertension, 47% of the patients had chronic kidney disease, and 45% reported smoking. In fact, 45% of the patients eventually suffered an amputation. We also found that the situation is more difficult because the great majority of the patients (96%) have a low level of education and very low income and they do not have any health insurance. Nevertheless, we also found that an efficient treatment can help in avoiding amputations, since 53% of grade IV and 25% of grade V lesions according to the Wagner system did not suffer an amputation. Conclusions: Therefore, an effective antibiotic treatment and an education of the patient on the adequate care of their lesions are essential in increasing the welfare of patients, especially when they have a low level of education.

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Section: Discussionsupporting

confidence: 88%

Clinical and surgical characteristics of infected diabetic foot ulcers in a tertiary hospital of Mexico

Cervantes-García

Salazar-Schettino

2017

Diabetic Foot & Ankle

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“…42 However, it is usually the combined effect of macrovascular and microvascular complications, comorbid conditions, and background demographic, clinical and treatment satisfaction variables which degrade HRQoL and not diabetes per se. 43 The results of the known-groups comparisons performed here conform to the literature 1,[12][13][14][15]17,[27][28][38][39][40][41] in terms of the score differences and the direction of these differences.…”

Section: Discussionsupporting

confidence: 77%

“…The overall results for the psychometric properties [38][39][40][41] but in the end their absence can be taken as evidence that the instrument is sensitive at its lower end. All SF-36 mean scale scores (not shown) were lower than the respective general population scores reported in the instrument validation study.…”

Section: Discussionmentioning

confidence: 95%

Validity and reliability of the Greek version of the Diabetic Foot Ulcer Scale - Short Form (DFS-SF)

Kontodimopoulos

Veniou

Tentolouris

et al. 2016

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ObJECTIvE: Diabetic foot ulcer is a critical and costly complication of diabetes mellitus. The aim of this study was to assess the psychometric properties of the greek version of the diabetic foot ulcer scale -short form (DFS-SF). DESIgN: a sample of patients with diabetic foot ulcer (N=110) was surveyed with the DFS-SF and various demographic and disease-related questions. The validated greek SF-36 instrument was used as a "gold standard" for health-related quality of life comparisons. hypothesized scale structure, internal consistency reliability (Cronbach's alpha) and various forms of construct validity (convergent, discriminative, concurrent and known -groups) were assessed. RESUlTS: multitrait scaling confirmed the scale structure of the DFS-SF, with 32 excellent item convergence (100%) and good discrimination (84.1%) rates. Cronbach's alpha was >0.70 for all scales. Spearman's correlations between similar DFS-SF and SF-36 scales ranged between 0.39-0.79 (p<0.001). Expected interscale correlations and knowngroups comparisons supported construct validity. CONClUSIONS: The observed psychometric properties of the greek DFS-SF imply suitability for assessing health-related quality of life in patients with diabetic foot ulcer. Future studies should focus on generalizability of the results, as well as on specific issues such as longitudinal validity and responsiveness.

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“…The SUV study is certainly one of the most important epidemiological investigations on vascular ulcers of lower limbs carried out in Italy in the recent years, because of the high quantity of data collected (1163 patients, of whom about 50% followed up until 9 months after start of therapy) and the widespread presence of participating centres (59 centres representing 14 Italian regions). Published epidemiological studies have been performed recently in leg ulcers in Romania and New Zealand , in diabetic ulcers in China , in hypertensive leg ulcers in France and in chronic leg wounds in Denmark ; to our knowledge, however, the SUV study is the only one that has involved more than one thousands patients affected by different types of leg ulcers (venous, arterial, diabetic, mixed, etc. ).…”

Section: Discussionmentioning

confidence: 99%

A large Italian observational multicentre study on vascular ulcers of the lower limbs (Studio Ulcere Vascolari)

Apollonio

Antignani²,

Salvo

et al. 2014

International Wound Journal

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An observational study of 2 years was promoted by the Italian Association for Cutaneous Ulcers (AIUC) in order to monitor the epidemiology of leg ulcers, the trend of healing and the more frequent therapeutic approaches in lower limb ulcers. Fifty-nine sites in 14 different Italian regions involved in the study, with 1333 enrolled patients (1163 patients fully evaluated and followed up for 9 months). A prevalence of females (62%) was observed with a mean age of 70 years and a high rate of hypertension (62%), diabetes (38%) and obesity (29%). Venous ulcer was most frequent (55%), followed by mixed (25%) and diabetic (8·3%) ulcers. Basically, all patients received a local therapy (LT) (compression and advanced local therapies), while 63% of patients have an associated systemic pharmaceutical treatment. Ulcer healing rates progressively increased throughout the study and despite the type of observational study does not allow conclusions on the treatment, it was observed that the patients receiving additional systemic drugs were associated with a more rapid acceleration of healing rates of ulcers compared to LT alone (3 months: 39·7% versus 29·2%; 6 months: 62·0% versus 47·0%; 9 months: 74·7% versus 63·8%). In particular, the Studio Ulcere Vascolari (SUV) study showed that a combination treatment with sulodexide and compression therapy allows for a greater increase in the healing rates in venous ulcers.

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The Investigation of Demographic Characteristics and the Health-Related Quality of Life in Patients With Diabetic Foot Ulcers at First Presentation

Cited by 22 publications

References 19 publications

Clinical and surgical characteristics of infected diabetic foot ulcers in a tertiary hospital of Mexico

Clinical and surgical characteristics of infected diabetic foot ulcers in a tertiary hospital of Mexico

Validity and reliability of the Greek version of the Diabetic Foot Ulcer Scale - Short Form (DFS-SF)

A large Italian observational multicentre study on vascular ulcers of the lower limbs (Studio Ulcere Vascolari)

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