The Intra-articular Effect of Various Postoperative Managements Following Knee Ligament Repair

Ogata, Kosuke; Whiteside, Leo A.; Andersen, David

doi:10.1097/00003086-198007000-00046

Cited by 47 publications

(13 citation statements)

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“…Animal studies have also shown that different ligaments heal at different rates [37,[68][69][70][71][72][73] and that combined ligament injuries heal at a slower rate than isolated injures and produce tissue of lower quality [37,68,69,[74][75][76][77][78]. More specifically, ACL and MCL structures tend to heal at varying rates comparatively, and the quality of remodeled tissue overall among different animal species remains inferior to that of normal ligaments [53,54,56,60,63,68,[79][80][81][82][83].…”

Section: Remodeled Ligaments -Not Nearly As Good As Newmentioning

confidence: 99%

Ligament Injury and Healing: A Review of Current Clinical Diagnostics and Therapeutics

Hauser¹

2013

TOREHJ

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Ligament injuries are among the most common causes of musculoskeletal joint pain and disability encountered in primary practice today. Ligament injures create disruptions in the balance between joint mobility and joint stability, causing abnormal force transmission through the joint, which results in damage to other structures in and around the joint. The long-term consequence of nonhealed ligament injury is osteoarthritis, the most common joint disorder in the world today.Ligaments heal through a distinct sequence of cellular events that take place in three consecutive stages: an acute inflammatory phase, a proliferative or regenerative phase, and a tissue remodeling phase. The process can take months to resolve itself, and despite advances in therapeutics, many ligaments do not regain their normal tensile strength.Various diagnostic procedures have been used to determine and assess ligament injury. Traditionally, MRI and X-rays have been the most utilized techniques; however, because ligaments do not show up clearly with these devices, there have been many false positives and negatives reported due to inconclusive or inaccurate readings. Newer technologies, such as ultrasound and digital motion X-ray, are able to provide a more detailed image of a ligament's structure and function.Numerous strategies have been employed over the years attempting to improve ligament healing after injury or surgery. One of the most important of these is based on the understanding that monitoring early resumption of activity can stimulate repair and restoration of function and that prolonging rest may actually delay recovery and adversely affect the tissue's response to repair. Likewise, there is a shift away from the use of steroid injections and nonsteroidal antiinflammatory medications. Although these compounds have been shown effective in decreasing the inflammation and pain of ligament injuries for up to six to eight weeks, their use has been shown to inhibit the histological, biochemical, and biomechanical properties of ligament healing. For this reason their use is cautioned against in athletes who have ligament injuries. Such products are no longer recommended for chronic soft tissue injuries or for acute ligament injuries, except for the shortest possible time, if at all.Regenerative medicine techniques, such as prolotherapy, have been shown, in both case series and clinical studies, to resolve ligament injuries of the spine and peripheral joints. More research and additional studies are needed to better assess ligament injuries and healing properties.

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Section: Remodeled Ligaments -Not Nearly As Good As Newmentioning

confidence: 99%

Ligament Injury and Healing: A Review of Current Clinical Diagnostics and Therapeutics

Hauser¹

2013

TOREHJ

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“…have not simulated the well-described clinical failure condition in which ligament ends become "mopped" after rupture (Kennedy et al 1976, Matyas andFrank 1990). Instead, experimental ligament injury has usually been induced by a simple transverse scalpel cut (Ogata et al 1980, Piper and Whiteside 1980, Woo et al 1987. It was postulated that increasing the ligament cut-end surface area by mop-ending may strengthen the entire healing bone-ligament-bone complex by increasing the area for functional attachments of a scar.…”

Section: No Effect Of Mop-ending On Ligament Healingmentioning

confidence: 99%

No effect of mop-ending on ligament healing: Rabbit studies of severed collateral knee ligaments

Chimich

Frank

Shrive

et al. 1993

Acta Orthopaedica Scandinavica

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“…Despite these findings, the optimal postoperative method and duration of tarsal immobilization in dogs is currently unknown. Research into ligamentous injuries in humans has suggested that prolonged rest or immobilization could in fact have adverse effects on tissue repair and healing and that early mobilization may actually stimulate repair and decrease the time required for adequate rehabilitation …”

Section: Discussionmentioning

confidence: 99%

The use of bidirectional barbed suture in the treatment of a complete common calcanean tendon rupture in a dog: Long‐term clinical and ultrasonographic evaluation

Frame

Ben‐Amotz

Simpler

et al. 2019

Clinical Case Reports

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The Intra-articular Effect of Various Postoperative Managements Following Knee Ligament Repair

Cited by 47 publications

References 0 publications

Ligament Injury and Healing: A Review of Current Clinical Diagnostics and Therapeutics

Ligament Injury and Healing: A Review of Current Clinical Diagnostics and Therapeutics

No effect of mop-ending on ligament healing: Rabbit studies of severed collateral knee ligaments

The use of bidirectional barbed suture in the treatment of a complete common calcanean tendon rupture in a dog: Long‐term clinical and ultrasonographic evaluation

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