The Internal Structure of Helical Pores Self‐Assembled from Dendritic Dipeptides is Stereochemically Programmed and Allosterically Regulated

Abstract

Wer die Natur beherrschen will: Die innere Struktur der helicalen Poren in Proteinmimetika, die selbstorganisiert aus Dendrit‐Dipeptid‐Hybriden entstehen, wird durch die Konfiguration des Dipeptids festgelegt und allosterisch gesteuert. Als erste synthetische supramolekulare Struktur mit helicalen Poren ist die Architektur sowohl in Lösung als auch im Festkörper stabil; zudem ähnelt die Schrittfolge bei ihrer Bildung einem natürlichen Prozess.

Thixotropic Twin‐Dendritic Organogelators

“…We demonstrate the importance of weak lateral hydrogen bonding within a column stratum versus hydrogen bonding along the length of the column for forming porous columnar mesophases and, by extension, thixotropic gels. Keywords: dendrimers · gels · liquid crystals · self-assembly · supramolecular chemistry form either cylindrical [4,5] or spherical [6][7][8] supramolecular dendrimers in bulk and solution. The supramolecular dendrimers self-organize in periodic [4][5][6][7][8] and quasiperiodic [8] arrays.…”

“…Keywords: dendrimers · gels · liquid crystals · self-assembly · supramolecular chemistry form either cylindrical [4,5] or spherical [6][7][8] supramolecular dendrimers in bulk and solution. The supramolecular dendrimers self-organize in periodic [4][5][6][7][8] and quasiperiodic [8] arrays. Symmetric twin-dendritic benzamides and dissymmetric Janus-dendritic benzamides undergo self-assembly to form periodic lattices and superlattices.…”

“…The design and convergent synthesis of the twin-dendritic organogelators are based upon our previously reported selfassembling dendrons [4][5][6][7][8] and twin-dendritic and Janus-dendritic benzamides. [9] Amphiphilic, self-assembling dendrons Abstract: Twin-dendritic organogelators have been prepared through selective functionalization of N-(3-aminopropyl)-1,3-propanediamine (APPDA) with self-assembling dendrons by using 1,1'-carbonyldiimidazole (CDI).…”

“…[9] Structural and retrostructural analysis of self-organized arrays in bulk by using a combination of techniques, including thermal optical polarized microscopy (TOPM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), and electron density mapping, allows us to elucidate the mechanisms by which self-assembly, self-organization, and subsequent functions arise. [4][5][6][7][8][9] In solution, structural and retrostructural analysis is achieved by using NMR, CD, and UV/Vis spectroscopies. [5] Results and Discussion Synthesis of the twin-dendritic organogelators: Twin-dendritic organogelators were designed by using N-(3-aminopropyl)-1,3-propanediamine (APPDA) and self-assembling monodendritic carboxylic acids.…”

“…[4][5][6][7][8][9] In solution, structural and retrostructural analysis is achieved by using NMR, CD, and UV/Vis spectroscopies. [5] Results and Discussion Synthesis of the twin-dendritic organogelators: Twin-dendritic organogelators were designed by using N-(3-aminopropyl)-1,3-propanediamine (APPDA) and self-assembling monodendritic carboxylic acids. Selective condensation of the primary amines with the dendritic carboxylic acids was desired.…”