The interconversion of glutamic acid and aspartic acid in respiring tissues

Abstract

of glyoxylate, or oxalate, in the presence of acetylcoenzyme A. 8. It is suggested that during growth on oxalate, the oxalate, possibly in the form ofoxalyl-coenzyme A, is reduced to glyoxylate, which is taken to be the precursor of glycine and phosphoglycerate. The phosphoglycerate formed then enters established routes of biosynthesis. We wish to thank Professor Sir Hans A. Krebs, F.R.S., for his interest and encouragement and Mrs M. Jenkins for her skilled technical assistance. This work was supported by the Rockefeller Foundation and by the Office of Scientific Research of the Air Research and Development Command of the United States Air Force, through its European Office, under contract no. AF. 61(052)-180, and was done while one of us (D. B. K.) held an Overseas Scholarship of the Commonwealth Scientific and Industrial Research Organization (Australia).

Preparation and Properties of Sweet Potato Mitochondria

“…The mechanism of inhibition remains unknown (17). The loss of antinmycin A inhibition caused by degradation of the inhibitor h1as been reported (28 (25) 298 (36) 288 (38) reported here fall within the range of those reported (23) for lupine mitochondria. VIII.…”

“…The supernatanit suspension fronm this centrifugation was centrifuged at 10.000 X g for 15 minutes andl the pellet x-as washed with a mixture of 0. 25 Mr sucrose and 0.37 alr imiannitol and resedimented by centrifuging at 10,000 X g for 15 minutes. The resulting pellet was carefully suspended in 0.5 M mannitol so that a minimal amount of starch was resuspended and then recentrifuged.…”

Metabolic Processes in Cytoplasmic Particles of the Avocado Fruit. VI. Controlled Oxidations and Coupled Phosphorylations

“…W\iskich and Bonner (29) (20) and that the oxygen uptake is due to the oxidation of a-ketoglutarate. In the presence of glutamate and arsenite the oxidation of malate was maintained, presumably due to the removal of oxaloacetate.…”

Concentrations of Nicotinamide Nucleotide Coenzymes in Micro-Organisms

“…Nocardia globerula (NCIB 8852) was maintained on PM agar slopes and grown on: a, the complex medium of Krebs & Bellamy (1960) or, b, the defined medium of Mencher & Heim (1962).…”