The Influence of the Addition of Collagen on the Rheological Properties of Chitosan Chloride Solutions

Owczarz, Piotr; Rył, Anna; Modrzejewska, Zofia; Dziubiński, M.

doi:10.15259/pcacd.22.18

Cited by 11 publications

(16 citation statements)

References 23 publications

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“…However, this increase in gelation temperature is not a monotonous function of collagen concentration. This confirms previous studies of thermosensitive hydrogels with the addition of bovine collagen [21]. Low protein concentration causes a temperature increase from 26.5 ° C to 37.4 ° C and 38.4 ° C respectively for samples 2 and 3.…”

Section: Resultssupporting

confidence: 91%

“…6. The negative effect of collagen addition on mechanical properties of chitosan hydrogels is consistent with the results of studies with bovine-derived collagen [21]. The obtained mechanical spectra at 35 °C were almost no different from the curves shown in Fig.…”

Section: Resultssupporting

confidence: 89%

“…More precisely, the addition of collagen causes a stronger domination of viscous properties over elastic ones in a wider range of angular frequency and reduction the mechanical strength. However, for all experimental curves, a shift toward a stronger domination of the highly elastic region on the theoretical curve [21,32] is observed. For all samples, the dominance area of elastic properties over viscous ones is stronger noted.…”

Section: Resultsmentioning

confidence: 77%

“…The study of thermosensitivity (changes in viscoelastic properties under the influence of heating) of colloidal chitosan-collagen solutions is discussed in detail in the paper [21]. In these studies, the authors concluded unequivocally negative effect of the addition of collagen on the mechanical properties of composite hydrogels obtained.…”

Section: Introductionmentioning

confidence: 99%

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Influence of fish collagen on viscoelastic properties and sol-gel phase transition of chitosan solutions

Rył

Owczarz

2018

Acta Innovations

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The thermosensitive hydrogels are widely used in tissue engineering due to their non-invasive application. Special interest of researchers, due to the specific characteristics of both materials, is aimed at composites of natural origin obtained from chitosan hydrogels combined with collagen. The mechanical properties of the thermosensitive chitosan-fish collagen hydrogels and the sol-gel phase transition parameters were determined by the rotational rheometry measurement techniques. Based on comparison of the obtained storage modulus G' curves, it was found that the addition of collagen negatively affects the mechanical properties of composite scaffolds. The addition of this protein substance decreases their elasticity. Only the smallest concentration (0.25g collagen/1 g chitosan) of collagen improves the mechanical properties of composite hydrogels, from 56 kPa to 61 kPa. Conducted non-isothermal studies allowed to conclude that the addition of collagen causes an increasing temperature of sol-gel phase transition. However, the observed changes are not a monotone function of the biopolymer concentration.

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Section: Resultssupporting

confidence: 91%

Section: Resultssupporting

confidence: 89%

Section: Resultsmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Influence of fish collagen on viscoelastic properties and sol-gel phase transition of chitosan solutions

Rył

Owczarz

2018

Acta Innovations

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“…The addition of calcium carbonate to sample 3 (which gives the composition of sample 3CC) results in the occurrence of characteristic shapes of the curves of storage G' and loss G" moduli, cf. Figure 6b-e, towards a stronger domination of the glass transition and glassy state regions [58][59][60]. The addition of calcium carbonate results in obtaining for sample 3CC similar experimental curves for storage G' and loss G" moduli that were obtained for sample 3 in the case of tests carried out at lower temperatures; cf.…”

Section: Enrichment With Calcium Ionssupporting

confidence: 69%

Injectable Chitosan Scaffolds with Calcium β-Glycerophosphate as the Only Neutralizing Agent

et al. 2019

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The presented work describes the method of preparation of thermosensitive chitosan hydrogels using calcium β-glycerophosphate salt as the only pH neutralizing agent and supporting the crosslinking process. The presence of calcium ions instead of sodium ions is particularly important in the case of scaffolds in bone tissue engineering. Rheological and physicochemical properties of low concentrated chitosan solutions with the addition of calcium β-glycerophosphate were investigated using rotational rheometry techniques, Zeta potential (by electrophoresis), XPS, and SEM analysis together with an EDS detector. It was found to be possible to prepare colloidal solutions of chitosan containing only calcium β-glycerophosphate (without sodium ions) undergoing a sol-gel phase transition at the physiological temperature of the human body. It has also been shown that it is possible to further enrich the obtained cellular scaffolds with calcium ions. Using the addition of calcium carbonate, hydrogels with a physiological ratio of calcium to phosphorus (1.6–1.8):1 were obtained.

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Thermoinduced aggegation of chitosan systems in perikinetic and orthokinetic regimes

Rył

Owczarz

2021

Carbohydrate Polymers

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The Influence of the Addition of Collagen on the Rheological Properties of Chitosan Chloride Solutions

Cited by 11 publications

References 23 publications

Influence of fish collagen on viscoelastic properties and sol-gel phase transition of chitosan solutions

Influence of fish collagen on viscoelastic properties and sol-gel phase transition of chitosan solutions

Injectable Chitosan Scaffolds with Calcium β-Glycerophosphate as the Only Neutralizing Agent

Thermoinduced aggegation of chitosan systems in perikinetic and orthokinetic regimes

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