The influence of salinity on acute nickel toxicity to the two euryhaline fish species, <i>Fundulus heteroclitus</i> and <i>Kryptolebias marmoratus</i>

Bielmyer, Gretchen K.; Decarlo, Carri; Morris, Cameron; Carrigan, Thomas P.

doi:10.1002/etc.2185

Cited by 31 publications

(6 citation statements)

References 35 publications

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“…Additionally, several aquatic organisms showed an increased tolerance to copper ions with increasing salinity [36]. Similar trends were observed for nickel [37] and zinc [38] in F. heteroclitus and Kryptolebias marmoratus .…”

Section: Introductionsupporting

confidence: 71%

Sublethal Effects of CuO Nanoparticles on Mozambique Tilapia (Oreochromis mossambicus) Are Modulated by Environmental Salinity

et al. 2014

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The increasing use of manufactured nanoparticles (NP) in different applications has triggered the need to understand their putative ecotoxicological effects in the environment. Copper oxide nanoparticles (CuO NP) are toxic, and induce oxidative stress and other pathophysiological conditions. The unique properties of NP can change depending on the characteristics of the media they are suspended in, altering the impact on their toxicity to aquatic organisms in different environments. Here, Mozambique tilapia (O. mossambicus) were exposed to flame synthesized CuO NP (0.5 and 5 mg·L−1) in two environmental contexts: (a) constant freshwater (FW) and (b) stepwise increase in environmental salinity (SW). Sublethal effects of CuO NP were monitored and used to dermine exposure endpoints. Fish exposed to 5 mg·L−1 CuO in SW showed an opercular ventilation rate increase, whereas fish exposed to 5 mg·L−1 in FW showed a milder response. Different effects of CuO NP on antioxidant enzyme activities, accumulation of transcripts for metal-responsive genes, GSH∶GSSG ratio, and Cu content in fish gill and liver also demonstrate that additive osmotic stress modulates CuO NP toxicity. We conclude that the toxicity of CuO NP depends on the particular environmental context and that salinity is an important factor for modulating NP toxicity in fish.

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Section: Introductionsupporting

confidence: 71%

Sublethal Effects of CuO Nanoparticles on Mozambique Tilapia (Oreochromis mossambicus) Are Modulated by Environmental Salinity

et al. 2014

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“…The overall low correlation between the sensitivities of embryos and RTgill-W1 cells may in part be explained by a matrix effect in the cell exposure media. Nickel toxicity has been shown to decrease with higher water hardness, possibly also due to complexation with chloride (Bielmyer et al, 2013). The comparatively high salt concentration of the medium used in the RTgill-W1 cultures may result in a reduction of chemical (i.e., metals) bioavailability via complexation with anions or competition with cations.…”

Section: Toxicity Model Correlationsmentioning

confidence: 99%

Fish Embryo Acute Toxicity Testing and the RTgill‐W1 Cell Line as In Vitro Models for Whole‐Effluent Toxicity (WET) Testing: An In Vitro/In Vivo Comparison of Chemicals Relevant for WET Testing

Scott

Grewe

Minghetti

2022

Enviro Toxic and Chemistry

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The fathead minnow (Pimephales promelas) fish embryo acute toxicity (FET) test was compared to the fish gill cells (RTgill‐W1) in vitro assay and to the fish larvae acute toxicity test to evaluate their sensitivity for whole‐effluent toxicity (WET) testing. The toxicity of 12 chemicals relevant for WET testing was compared as proof of principle. The concentrations lethal to 50% of a population (LC50) of embryos were compared to those in fish larvae and to the 50% effect concentration (EC50) in RTgill‐W1 cells from previous literature. Along with traditional FET endpoints (coagulation, somite development, tail detachment, and heartbeat), cardiotoxicity was evaluated for WET applicability. Heart rate was measured at LC20 and LC50 values of six subselected chemicals (Cd, Cu, Ni, ammonia, 3,4‐dichloraniline, and benzalkonium chloride). In addition, the toxicity of Cd and Ni was evaluated in RTgill‐W1 cells exposed in a hypoosmotic medium to evaluate the effect that osmolarity may have on metal toxicity. A significant correlation was found between the FET and larvae LC50 values but not between the RTgill‐W1 EC50 and FET LC50 values. Although sensitivity to Ni and Cd was found to increase with hypoosmotic conditions for FET and RTgill‐W1 cells, a correlation was only found with removal of Ni from the analysis. Hypoosmotic conditions increased sensitivity with a significant correlation between RTgill‐W1 cells and larvae. Cardiotoxicity was shown in three of the five subselected chemicals (Cd, Cu, and 3,4‐dichloroaniline). Overall, both in vitro alternative models have shown good predictability of toxicity in fish in vivo for WET chemicals of interest. Environ Toxicol Chem 2022;41:2721–2731. © 2022 SETAC

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“…Similar to marine fish, sensitivity of tropical and temperate estuarine fish (both adults and juveniles) to nickel is low, with most studies demonstrating effects above 1 mg/L (Denton and Burdon-Jones 1986;Bielmyer et al 2013). A few studies have investigated the toxicity of nickel to estuarine crustaceans, but these were scored as lower quality or failed the quality assurance assessment.…”

Section: Estuarinementioning

confidence: 99%

A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region

Gissi

Stauber

Binet

et al. 2016

Environmental Pollution

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. (2016). A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region. Environmental Pollution, 218 1308Pollution, 218 -1323 A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region AbstractThe South East Asian Melanesian (SEAM) region contains the world's largest deposits of nickel lateritic ores. Environmental impacts may occur if mining operations are not adequately managed. Effects data for tropical ecosystems are required to assess risks of contaminant exposure and to derive water quality guidelines (WQG) to manage these risks. Currently, risk assessment tools and WQGs for the tropics are limited due to the sparse research on how contaminants impact tropical biota. As part of a larger project to develop appropriate risk assessment tools to ensure sustainable nickel production in SEAM, nickel effects data were required. The aim of this review was to compile data on the effects of nickel on tropical marine, estuarine, pelagic and benthic species, with a particular focus on SEAM. There were limited high quality chronic nickel toxicity data for tropical marine species, and even fewer for those relevant to SEAM. Of the data available, the most sensitive SEAM species to nickel were a sea urchin, copepod and anemone. There is a significant lack of high quality chronic data for several ecologically important taxonomic groups including cnidarians, molluscs, crustaceans, echinoderms, macroalgae and fish. No high quality chronic nickel toxicity data were available for estuarine waters or marine and estuarine sediments. The very sparse toxicity data for tropical species limits our ability to conduct robust ecological risk assessment and may require additional data generation or readacross from similar species in other databases (e.g. temperate) to fill data gaps. Recommendations on testing priorities to fill these data gaps are presented. Capsule abstractNickel toxicity data is lacking for tropical marine biota; data is required for key taxa including cnidarians, molluscs, crustaceans, echinoderms, macroalgae and fish. HighlightsSouth East Asia and Melanesia contains the largest deposits of nickel lateritic ores Environmental impacts may occur if mining operations are not adequately managed Risk assessment tools for nickel in the tropics are limited due to lack of data We compiled nickel data for aquatic tropical ecosystems and identified key gaps Nickel data is required for corals, molluscs, crustaceans, echinoderms, macroalgae, fish KeywordsMining, tropical ecotoxicology, ecological risk assessment, bioassay, species sensitivity distribution. 2 AbstractThe South East Asian Melanesian (SEAM) region contains the world's largest deposits of nickel lateritic ores. Environmental impacts may occur if mining operations are not adequately managed. Effects data for tropical ecosystems are required to assess risks of contaminant exposure and to derive water quality ...

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The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus

Cited by 31 publications

References 35 publications

Sublethal Effects of CuO Nanoparticles on Mozambique Tilapia (Oreochromis mossambicus) Are Modulated by Environmental Salinity

Sublethal Effects of CuO Nanoparticles on Mozambique Tilapia (Oreochromis mossambicus) Are Modulated by Environmental Salinity

Fish Embryo Acute Toxicity Testing and the RTgill‐W1 Cell Line as In Vitro Models for Whole‐Effluent Toxicity (WET) Testing: An In Vitro/In Vivo Comparison of Chemicals Relevant for WET Testing

A review of nickel toxicity to marine and estuarine tropical biota with particular reference to the South East Asian and Melanesian region

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