The influence of pH and temperature on the morphology of hydroxyapatite synthesized by hydrothermal method

Liu, Jingbing; Ye, Xiaoyue; Wang, Hao; Zhu, Ming‐Qiang; Wang, Bo; Yan, Hui

doi:10.1016/s0272-8842(02)00210-9

Cited by 280 publications

(158 citation statements)

References 11 publications

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“…Therefore, different production methods were reported such as mechanochemistry [3,4], ultrasonic irradiation [5], microwave irradiation [6,7], sol-gel [8][9][10][11], chemical precipitation [12,13], hydrothermal method [14][15][16], hydrolysis [17], microemulsion [18][19][20], and emulsion liquid membrane [21]. The synthesized HAp does not have adequate biological properties as the natural apatite existing in bones.…”

Section: Introductionmentioning

confidence: 99%

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Barakat

Khalil

Sheikh

et al. 2008

Materials Science and Engineering: C

160

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Section: Introductionmentioning

confidence: 99%

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Barakat

Khalil

Sheikh

et al. 2008

Materials Science and Engineering: C

160

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“…So it is worth investigating feasibility of oriented structure derived by organized crystal growth of HAp, since rod-shaped HAp single crystal could be obtained by a hydrothermal processing. 6,7) Morphology of HAp crystals formed under hydrothermal condition are affected by some factors such as solubility of starting material, processing temperature, 8) pH of solvent 9) and additives in the solvent. 10) In this study, we focused on homogeneous reactivity of crystal plane of calcite single crystal, to achieve spontaneous formation of oriented crystals of HAp through uniform reaction of calcium of calcite with phosphate ions in the surrounding fluid.…”

Section: Introductionmentioning

confidence: 99%

Formation of Oriented Hydroxyapatite Rods by Hydrothermal Treatment of Calcite Single Crystal

Kim¹,

Kikuta²,

Ohtsuki³

2012

Korean. J. Mater. Res.

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Morphological control on hydroxyapatite crystals has attractive prospects in research to clarify the effects of crystal planes on biological performance. Hydrothermal processing is known as a typical type of processing for fabricating well-grown crystals with unique morphology. The purpose of the present study is to examine the feasibility of well-crystallized crystals with oriented structures through hydrothermal treatment of calcite. A single crystal of calcite was applied to hydrothermal treatment in a phosphate solution at 160 o C. Rod-shaped hydroxyapatite crystals with micrometer-size were formed on the {100} face of calcite after treatment, while nanometer-sized hydroxyapatite crystals were formed on the (111). The hydroxyapatite crystals formed on each plane were not morphologically changed with increasing treatment periods. An oriented structure of rod-shaped hydroxyapatite was constructed after hydrothermal treatment of {100} planes on the calcite single, while such orientation was not observed on the (111) plane after the treatment. The layer of hydroxyapatite formed on the {100} plane was thicker than that of the (111) plane. The {100} plane of calcite shows a higher reactivity than that of the (111) plane, which results in rapid crystal growth of hydroxyapatite. The difference in the morphology of the formed hydroxyapatite was governed by the reactivity of each crystal plane exposed to the surrounding solution.

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“…[18][19][20][21][26][27][28][29] It is known that HAp nanorods can be synthesized; however, the preparation of nano-sized particles with high aspect ratio, appropriate stoichiometry and high crystallinity still remains an important task. 4,5,[19][20][21][25][26][27][28][29][30][31][32] The hydrothermal method, which works at high temperature and high pressure, is the most frequently used technique for one-dimensional growth of HAp. This method enables the synthesis of HAp powders with high degree of crystallinity which are relatively stable in physiological medium.…”

Section: Introductionmentioning

confidence: 99%

“…For instance, some works show that the rod-like HAp is synthesized in acidic 5,35 or approximately neutral conditions, 28 and others show that these nanorods are synthesized under alkaline conditions. [30][31][32]36 Moreover, only few experimental parameters were evaluated in each study.…”

Section: Introductionmentioning

confidence: 99%

Design of experiments (DOE) for the optimization of hydrothermal synthesis of hydroxyapatite nanoparticles

Sadat‐Shojai¹,

Atai²,

Nodehi³

2011

J. Braz. Chem. Soc.

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O objetivo deste trabalho foi investigar a influência de diversos parâmetros de reação sobre as propriedades de nanopartículas de hidroxiapatita (HAp) preparadas pelo método hidrotérmico. Os dados da literatura descrevem condições experimentais variadas para a síntese hidrotérmica de HAp. Uma abordagem específica foi então utilizada para avaliar os fatores estatisticamente influentes entre aqueles descritos na literatura. O papel de cada parâmetro experimental também foi discutido no contexto da nucleação de partículas e do mecanismo de crescimento de cristais. Dentro das variáveis selecionadas, temperatura e pH foram os fatores que mais afetaram a composição e morfologia da HAp. Além disso, neste estudo, diferentes morfologias variando de nanopartículas cilíndricas do tipo bastonete a esféricas com várias características foram obtidas com sucesso, o que pode ser aplicável na preparação de várias biocerâmicas de HAp.The aim of this work was to investigate the influence of different reaction parameters on the properties of hydroxyapatite (HAp) nanoparticles prepared by the hydrothermal method. The literature data describe widely different experimental conditions for the hydrothermal synthesis of HAp. A specific approach was therefore used to evaluate the statistically influential factors among those described in the literature. The role of each experimental parameter was also discussed within the framework of particle nucleation and crystal growth mechanism. Among the selected variables, temperature and pH were found to be the most significant factors affecting the composition and morphology of the HAp. Moreover, in the present study, different morphologies ranging from rod-like to spherical nanoparticles with various characteristics were successfully obtained, which can be applicable for the preparation of various HAp bioceramics.

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The influence of pH and temperature on the morphology of hydroxyapatite synthesized by hydrothermal method

Cited by 280 publications

References 11 publications

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Physiochemical characterizations of hydroxyapatite extracted from bovine bones by three different methods: Extraction of biologically desirable HAp

Formation of Oriented Hydroxyapatite Rods by Hydrothermal Treatment of Calcite Single Crystal

Design of experiments (DOE) for the optimization of hydrothermal synthesis of hydroxyapatite nanoparticles

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