Abstract-To obtain safe, environmental and economical benefits of machining, the research has been carrying out to reduce the use of cutting fluid during machining. One of the alternatives to dry and flooded machining is Minimum Quantity Lubrication from the point of cost, ecology and human health issues. This paper deals with the optimization of process parameters in turning of Titanium alloy (Ti-6Al-4V) under different machining conditions using Taguchi's Robust Design Methodology on tool wear. The control factors selected are type of machining environment, cutting speed, feed rate, depth of cut and type of carbide tool material. From Analysis of Means, it is found MQL and uncoated tool shown in better performance on reduction of tool wear rate. From the Analysis of Variance (ANOVA), it is found that the cutting speed has more influence in optimizing the tool wear rate.