The influence of microbial factors on the stability of the colloidal properties of urine in urolithiasis

Introduction. Urolithiasis is a multifactorial recurrent disease, unevenly spread throughout the world and characterizedby the formation of urinary stones of various chemical compositions, depending on pathogenesis, etiological, and epidemiological risk factors. Understanding the composition of chemicals and their prevailing ratios can help make decisions about treatment tactics, preventive measures to reduce the risk of recurrence and the prevalence of urolithiasis.Purpose of the study. To assess the distribution of chemical components in urinary stones along with an analysis of their population significance.Materials and methods. The urinary stones were obtained from 2854 patients with urolithiasis. The composition of urinary stones was analyzed by using an infrared spectroscopy method.Results. The predominance of oxalate stones was determined in multicomponent kidney stones (83,7%) and the prevalence of urate stones (54,2%) was revealed in monocomponent kidney stones. Urinary stones with a predominance of oxalates contained significantly fewer impurities (12.4%) than urinary stones with a predominance of urates, phosphates and carbonates with an average amount of impurities >24.0%.Conclusion. The analysis of urinary stones distribution based on pathogenic factors showed that the calcium metabolism disturbances prevail in the population of the Russian Federation (88.0%).

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The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis

Lebedev

Smirnova

Лапин

et al. 2021

Vestn. urol.

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Clinical and morphological of diagnostics and surgical tactics in the treatment of patients with secondary nephrolithiasis by renal parenchymal dysplasia on the background of renal failure caused in children

Safedov,

Azizov,

Badalov

et al. 2024

jour

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The purpose of the study. Improving the results of diagnosis and surgical treatment of patients with secondary nephrolithiasis by renal parenchymal dysplasia on the background of renal failure caused in children.Material and research methods. Clinic of Pediatric Surgery, Avicenna TSMU Abualiibn Sino analyzed 34 patients with renal failure of calculous etiology. In all cases, the biopsy was taken from the cortex – medulla of the kidney during nephrotomy, and during pyelotomy from the site of the nephrostomy tube. Studies of biopsy materials were carried out in laboratorits at the departments of histology, anatomy and oncology.Research results. We analyzed the results of a morphological study of 34 patients with CKD of calculous etiology. Chronic calculous pyelonephritis was detected in 32 (94,1%) patients, in whom the diagnoses coincided with the clinical and morphological ones. Of these, dysplasia of the renal parenchyma was detected in 8 patients. In 2 patients, histological examination did not reveal structural changes, possibly a biopsy was taken from healthy areas of the kidney tissue, although clinically and laboratory 100% calculous pyelonephritis occurred.Conclusion. Thus, in case of obstructive-calculous pyelonephritis, against the background of dysplasia of the kidney parenchyma, early clinical and morphological diagnostics, radical decompressive and sanitation surgery with reliable external urine wood is restored, the process of further wrinkling of the kidney is suspended.

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The influence of microbial factors on the stability of the colloidal properties of urine in urolithiasis

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The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis

The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis

Clinical and morphological of diagnostics and surgical tactics in the treatment of patients with secondary nephrolithiasis by renal parenchymal dysplasia on the background of renal failure caused in children

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