The Influence of Left Ventricle Diastolic Function on Natriuretic Peptides Levels in Patients with Atrial Fibrillation

Bąkowski, Dawid; Wożakowska−Kapłon, Beata; Opolski, Grzegorz

doi:10.1111/j.1540-8159.2009.02360.x

Cited by 27 publications

(19 citation statements)

References 29 publications

(33 reference statements)

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“…Given the short half-life of BNP (23 min), its level significantly declined 2 h after AF recovered. This decrease was sustained until three months after the surgery, which indicates that the left atrial structure can undergo reverse remodeling after ablation (Ari et al, 2008;Bakowski et al, 2009;Kallergis et al, 2010;Wozakowska-Kapłon et al, 2010;Wozakowska-Kapłon, 2010). In the recurrent group, BNP levels were significantly higher than that in the successful group before ablation (P < 0.01) and significantly decreased 2 h after ablation (P < 0.01).…”

Section: Discussionmentioning

confidence: 99%

Clinical significance and levels of blood brain natriuretic peptides in patients with persistent atrial fibrillation before and after catheter ablation

Sy¹,

Hl²,

Ps³

et al. 2015

Genet. Mol. Res.

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ABSTRACT. The aim of this study was to observe levels of blood brain natriuretic peptides (BNPs) in patients with persistent atrial fibrillation (AF) before and after catheter ablation. Thirty-six patients with persistent AF (28 successful surgeries and eight recurrent cases) and 36 healthy controls with normal sinus rhythm were recruited for this study. BNP levels in the AF and control groups were measured before and after catheter ablation. BNP levels before surgery were significantly higher in the persistent AF group than in the control group (P < 0.01). The successful surgery group had distinctly lower BNP levels before ablation than the recurrent group (P < 0.01). In the recurrent group, BNP levels 2 h after ablation were significantly lower than those before ablation (P < 0.01); these levels increased after AF recurrence (P < 0.01) and were comparable with those before ablation (P < 0.01). Logistic regression analysis indicated that the BNP level was an inde-S.Y. Xing et al. 6954©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (2): 6953-6959 (2015) pendent factor for and predictor of AF recurrence (P < 0.01). The BNP level in patients with persistent AF is clinically important in predicting and evaluating AF recurrence after ablation.

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Section: Discussionmentioning

confidence: 99%

Clinical significance and levels of blood brain natriuretic peptides in patients with persistent atrial fibrillation before and after catheter ablation

Sy¹,

Hl²,

Ps³

et al. 2015

Genet. Mol. Res.

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show abstract

“…2). It has been speculated that baseline diastolic LV dysfunction may account for this observation [16]. However, this has not been established since Doppler echocardiography was not routinely performed to evaluate diastolic function.…”

Section: Discussionmentioning

confidence: 95%

Steady-state B-type natriuretic peptide levels in patients with atrial fibrillation of various clinical backgrounds

Sadanaga¹,

Mitamura

Kohsaka

et al. 2011

Heart Vessels

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B-type natriuretic peptide level is increased in patients with atrial fibrillation. The aim of the present study was to present the distribution of steady-state B-type natriuretic peptide levels of various clinical backgrounds and to elucidate the usefulness of measuring them in patients with atrial fibrillation. B-type natriuretic peptide was measured in stable conditions in patients with atrial fibrillation (74 ± 10 y/o, n = 473). The average B-type natriuretic peptide level was 161 ± 202 (median 101) pg/ml. Multiple regression analysis showed that age, left ventricular ejection fraction, left atrial diameter, structural heart disease, chronic atrial fibrillation, and heart failure symptoms were independently associated with elevated B-type natriuretic peptide levels. However, in chronic atrial fibrillation patients without structural heart disease, B-type natriuretic peptide levels did not differ between those with and without heart failure symptoms. Notably, B-type natriuretic peptide levels were high (≥ 150 pg/ml) in 41% of asymptomatic chronic atrial fibrillation without structural heart disease. Steady-state B-type natriuretic peptide levels of various clinical backgrounds were presented. Contributions of BNP elevation by clinical variables were somewhat different in different population. B-type natriuretic peptide was elevated in substantial percentage of asymptomatic chronic atrial fibrillation even without structural heart disease.

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“…BNP levels of patients with AF have been reported to be elevated, and they were associated with left ventricle diastolic dysfunction [13,14]. We also showed that BNP levels in acute stroke patients with AF were elevated, which indicated that such patients might have heart failure in the acute phase of stroke [15].…”

Section: Introductionmentioning

confidence: 82%

The combination of elevated BNP and AF as a predictor of no early recanalization after IV-t-PA in acute ischemic stroke

Kimura

Shibazaki

Iguchi

et al. 2010

Journal of the Neurological Sciences

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The Influence of Left Ventricle Diastolic Function on Natriuretic Peptides Levels in Patients with Atrial Fibrillation

Abstract: The increase of ANP/BNP concentration in patients with AF results not only from the presence of AF, but also reflects the impaired LV diastolic function. Natriuretic peptides, especially BNP, may be useful in diagnosing LV diastolic dysfunction in patients with AF.

Cited by 27 publications

References 29 publications

Clinical significance and levels of blood brain natriuretic peptides in patients with persistent atrial fibrillation before and after catheter ablation

Clinical significance and levels of blood brain natriuretic peptides in patients with persistent atrial fibrillation before and after catheter ablation

Steady-state B-type natriuretic peptide levels in patients with atrial fibrillation of various clinical backgrounds

The combination of elevated BNP and AF as a predictor of no early recanalization after IV-t-PA in acute ischemic stroke

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