The Influence of Hostility and Family History of Cardiovascular Disease on Autonomic Activation in Response to Controllable versus Noncontrollable Stress, Anger Imagery Induction, and Relaxation Imagery

Addition is a chronic relapsing illness affected by multiple social, individual and biological factors that significantly impact course and recovery of the illness. Stress interacts with these factors and increases addiction vulnerability and relapse risk, thereby playing a significant role in the course of the illness. This paper reviews our efforts in developing and validating laboratory models of stress and drug cue-related provocation to assess stress responses and stress-related adaptation in addicted individuals compared with healthy controls. Empirical findings from human laboratory and brain imaging studies are presented to show the specific stress-related dysregulation that accompanies the drug-craving state in addicted individuals. In order to adequately validate our laboratory model, we have also carefully examined relapse susceptibility in the addicted individuals and these data are reviewed. The overarching goal of these efforts is to develop a valid laboratory model to identify the stress-related pathophysiology in addiction with specific regard to persistent craving and compulsive seeking. Finally, the significant implications of these findings for the development of novel treatment interventions that target stress processes and drug craving to improve addiction relapse outcomes are discussed.

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“…1999). They have also been used for anger provocation to assess anger effects on markers of cardiovascular disease (Nelson et al . 2005).…”

Section: Developing a Valid Laboratory Model To Study Stress And Drugmentioning

confidence: 99%

Modeling stress and drug craving in the laboratory: implications for addiction treatment development

2008

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“…High levels of hostility have been strongly associated with the development of cardiovascular disease (CVD; Naiura et al, 2002;Smith, 1994;Smith & Ruiz, 2002), increased cardiovascular reactivity to stressful situations (Rhodes, Harrison, & Demaree, 2002;Smith, Glazer, Ruiz, & Gallo, 2004), and higher resting levels of systolic blood pressure (SBP) and heart rate (HR; Keefe, Castell, & Blumenthal, 1986). Increased risk for hypertension and CVD among hostile individuals has been well documented (Nelson et al, 2005;Zhu et al, 2005), indicating a need for further research examining the effects of hostility level as a function of exposure to stress.…”

mentioning

confidence: 99%

An extension of the functional cerebral systems approach to hostility: A capacity model utilizing a dual concurrent task paradigm

Holland

Carmona

Harrison

2012

Journal of Clinical and Experimental Neuropsychology

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Regulatory control of emotions and expressive fluency (verbal or design) have historically been associated with the frontal lobes. Moreover, research has demonstrated the importance of cerebral laterality with a prominent role of the right frontal regions in the regulation of negative affect (anger, hostility) and in the fluent production of designs rather than verbal fluency. In the present research, participants identified with high and with low levels of hostility were evaluated on a design fluency test twice in one experimental session. Before the second administration of the fluency test, each participant underwent physiological (cold pressor) stress. It was hypothesized that diminished right frontal capacity in high-hostile men would be evident through lowered performance on this cognitive stressor. Convergent validity of the capacity model was supported wherein high-hostile men evidenced reduced delta magnitude over the right frontal region after exposure to the physiological stressor but failed to maintain consistent levels of right cerebral activation across conditions. The results suggest an inability for high-hostile men to maintain stable levels of cerebral activation after exposure to physiological and cognitive stress. Moreover, low-hostiles showed enhanced cognitive performance on the design task with lower levels of arousal (heightened delta magnitude). In contrast, reduced arousal yielded increased executive deficits in high-hostiles as evidenced through increased perseverative errors on the design fluency task.

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“…Because of the relationship between stress and CVD, it is important that stress management interventions have a relaxation component (Friedman, Myers, Krass, & Benson, 1996; Hui, Wan, Chan, & Yung, 2006; Keyworth et al, 2014; Nelson et al, 2005). These components include diaphragmatic breathing, progressive muscle relaxation, mindfulness, and meditation techniques.…”

Section: Psychosocial Intervention Approachesmentioning

confidence: 99%

An exploratory pilot of “A Mindful Heart”: A group-based approach for stress management in primary care.

Ogbeide

2018

Practice Innovations

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Psychosocial stress has been considered a contributing factor to the development and maintenance of hypertension. "A Mindful Heart" is a group-based intervention developed for stress management in patients who are hypertensive or prehypertensive. This program was designed to address a gap in the field of behavioral health; specifically, the need for brief, group-based interventions for primary care settings. The goal of this project was to determine intervention feasibility in the primary care setting. The group was conducted with 8 primary care patients who were low-income with hypertension. Assessments were conducted pre-and posttreatment. Improvements were found in multiple, self-report domains but not blood pressure (e.g., perceived stress, perceived physical health status, perceived mental health status). Despite study methodology limitations, the intervention feasibility is promising for the primary care setting. Clinical Impact StatementThis study advances the idea of the feasibility of a brief group intervention to promote stress management for patients at risk for cardiovascular disease in a primary care setting. Additionally, this study highlights the impact of a brief intervention on perceived health status for patients at risk for cardiovascular disease.

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The Influence of Hostility and Family History of Cardiovascular Disease on Autonomic Activation in Response to Controllable versus Noncontrollable Stress, Anger Imagery Induction, and Relaxation Imagery

Cited by 13 publications

References 30 publications

Modeling stress and drug craving in the laboratory: implications for addiction treatment development

Modeling stress and drug craving in the laboratory: implications for addiction treatment development

An extension of the functional cerebral systems approach to hostility: A capacity model utilizing a dual concurrent task paradigm

An exploratory pilot of “A Mindful Heart”: A group-based approach for stress management in primary care.

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