The influence of hepatitis B virus (HBV) or hepatitis C virus (HCV) infections on the pregnancy course

Nikolajuk-Stasiuk, Julita

doi:10.5603/gp.a2020.0139

Cited by 3 publications

(3 citation statements)

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“…In addition, sample representative and the data quality might effect the prevalence. Efforts on HBV prevention should not be relaxed since only 1% to 7% of pregnant women were HBV positive 38 . We cannot take it lightly regarding child prevention and control of hepatitis B infection.…”

Section: Discussionmentioning

confidence: 99%

“…Efforts on HBV prevention should not be relaxed since only 1% to 7% of pregnant women were HBV positive. 38 We cannot take it lightly regarding child prevention and control of hepatitis B infection. Preventive measurements on hepatitis B should be maintained and kept attachment of great importance.…”

Section: The Burden Of Hepatitis B Infection In Children Under Five H...mentioning

confidence: 99%

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Changes and gaps of global and regional disease burden of hepatitis B infection in children younger than 5 years old between 2015 and 2019: A real‐world data review

Wang,

Zhang,

Zhao

et al. 2023

Journal of Medical Virology

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Hepatitis B virus (HBV) infection has been declared an ongoing health threat, especially infections among children. We compared and updated the disease burden of HBV infection and the effectiveness of vaccination among children younger than 5 years to offer indications for hepatitis B prevention across the world. The country‐level data on the prevalence of hepatitis B surface antigen (HBsAg), the coverages of hepatitis B vaccine birth‐dose (HepB‐BD), three‐dose series (HepB3), income level, population density/size, and human development index were collected from open access databases including WHO, UNICEF, and World Bank. Comparison of the prevalence of HBsAg under 5 years old between 2015 and 2019 based on vaccination coverages was conducted by the gamma generalized linear mixed model. Globally, more than 6.3 million HBV infections were estimated in children under 5 years in 2019, compared to 10.1 million in 2015 within the 179 countries involved. The pooled average prevalence of HBsAg among children younger than 5 years decreased from 1.4% (95% confidence interval [CI]: 1.1–1.8) to 0.9% (95% CI: 0.7–1.2). The rate difference or rate ratio was −0.5% (95% CI: −0.6% to −0.3%) or 0.51(95% CI: 0.44–0.58), respectively. Countries from the African region or with lower income/population density/human development indexes bore the most significant disease burden of hepatitis B. Higher coverages of hepatitis B vaccine birth‐dose or primary series correlated with significant HBsAg prevalence decreases and much‐decreased ratio, independently. Hepatitis B prevention among children under 5 years has significantly been achieved while remaining the most life‐threatening disease burden, unequally distributed worldwide. The hepatitis B vaccination should be prioritized for all newborns, especially in those resource‐constrained countries or regions.

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Section: Discussionmentioning

confidence: 99%

Section: The Burden Of Hepatitis B Infection In Children Under Five H...mentioning

confidence: 99%

Changes and gaps of global and regional disease burden of hepatitis B infection in children younger than 5 years old between 2015 and 2019: A real‐world data review

Wang,

Zhang,

Zhao

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

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“…Abdominal stretching and leg edema together with increased sweat gland activity might also predispose to skin xerosis. Other possible causes of CP of non-lesional skin in pregnancy include hypothyroidism (1.02%) and chronic hepatitis B and C virus infection (0.34%) [ 2 , 127 ].…”

Section: Other Pruritic Conditions In Pregnancymentioning

confidence: 99%

Pruritus in Pregnancy

et al. 2022

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Pruritus in pregnancy is a common and burdensome symptom that may be a first sign of a pregnancy-specific pruritic disease (atopic eruption of pregnancy, polymorphic eruption of pregnancy, pemphigoid gestationis, and intrahepatic cholestasis in pregnancy) or a dermatosis coinciding with pregnancy by chance. Despite its high prevalence, pruritus is often underrated by physicians, and data regarding the safety profiles of drugs for pruritus are very limited. In this review, we illustrate the epidemiology, possible pathophysiology, clinical characteristics, and diagnostic workup of various pregnancy-related diseases and discuss antipruritic treatments. The prevalence of pruritus in pregnancy demonstrates the importance of symptom recognition and the need for an holistic approach, taking into account both the potential benefits for the patient and the potential risks to the fetus.

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Role of viral hepatitis in pregnancy and its triggering mechanism

Wu,

Wang,

Xiang

et al. 2024

Journal of Translational Internal Medicine

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Hepatitis viral infection can cause severe complications, even mortality in pregnant women and their offspring. Multiple studies have shown that vertical transmission can cause viral hepatitis infections in newborns, especially in hepatitis B, C, and E. Screening for hepatitis viral infection in pregnant women is essential. Once infected, pregnant women should be given timely antiviral treatments, which could effectively alleviate the disease progression and reduce adverse outcomes. Besides, the mechanism of viral hepatitis mediating adverse pregnancy outcomes has been a hot topic. Hepatitis B virus has been found to mediate both mother- to-child and parent-child transmission. Liver injury in hepatitis C virus infection is associated with immune-mediated mechanisms, which can be regulated by hormonal factors as well. The mediating mechanism of adverse maternal and infant outcomes caused by hepatitis E virus infection is mainly related to viral replication in the placenta and changes in cytokine and estrogen. Nevertheless, the specific mechanisms related to hepatitis A virus and hepatitis D virus remain unclear, and more research is needed. This review shows that the existence of viral hepatitis during pregnancy can pose certain risks for pregnant women and infants, and different interventions have been used to treat pregnant women infected with viral hepatitis. It may provide deep insight into adverse pregnancy outcomes caused by viral hepatitis and give guidance on treatment.

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The influence of hepatitis B virus (HBV) or hepatitis C virus (HCV) infections on the pregnancy course

Cited by 3 publications

References 0 publications

Changes and gaps of global and regional disease burden of hepatitis B infection in children younger than 5 years old between 2015 and 2019: A real‐world data review

Changes and gaps of global and regional disease burden of hepatitis B infection in children younger than 5 years old between 2015 and 2019: A real‐world data review

Pruritus in Pregnancy

Role of viral hepatitis in pregnancy and its triggering mechanism

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