The influence of CSN3 and LGB polymorphisms on milk production and chemical composition in Romanian Simmental cattle

Abstract

The aim of this study was to assess the influence of genotypes from the CSN3 and LGB loci on milk production and chemical composition in Romanian Simmental cattle (n=114). For the CSN3 locus a significantly higher frequency (P≤0.001) was observed for the allele A (0.785) compared to allele B (0.215) and for AA (0.631) compared to AB (0.307) and BB (0.062) genotypes, respectively. The AA genotype was associated with a higher milk production (5887.76±115.7 kg) compared to the yields associated with the BB genotype (5619±86.34 kg, P≤0.003), as well as a higher fat percentage (4.19±0.05% vs. 4.01±0.02%, P≤0.001). A higher milk protein percentage was associated with BB (3.4±0.02%) compared to AA (3.27±0.03) and AB (3.29±0.03) genotypes, respectively (P≤0.05). For the LGB locus, the frequency of allele A was significantly higher (0.606, P≤0.008) than allele B (0.394). The AB genotype was the most prevalent in the herd (0.579) compared to AA (0.316) and BB genotypes (0.105). The AB genotype was associated with a higher milk production (5906.54±166.76 kg) compared with the other two genotypes (P≤0.05). The BB genotype was associated with a higher fat percentage in milk (4.23±0.06%) compared with AA (4.17±0.06) and AB (4.2±0.08) genotypes, respectively (P≤0.01). For the LGB locus, no significant differences (P>0.05) were observed for milk protein percentage. In order to increase the quantity and quality of milk, the outcomes obtained in this study encourage improving genetic structure in cattle based on marker assisted selection for genes with economic values.

Polymorphisms in CSN3, CSN2 and LGB Genes and Their Relation to Milk Production in Dairy Cattle in the Czech Republic

“…In fact, identical results for Czech Simmental cattle were reported by Kučerová et al (2006) and Bartoňová et al 2012). Neamt et al (2017) discovered the marked predominance of the A allele (0.785) above the B allele (0.215). Research of Trakovická et al, 2012) reported similar results.…”

“…The same genotype order was also described in Holstein crossbred cows in the study of Molee et al (2015), AB 0.535, BB 0.289 and AA 0.175. The AB genotype was discovered to be the most frequent also in the study of Neamt et al (2017). The LGB gene was the only gene included in our analysis not to be in HWE.…”

“…I). In a number of studies, the AA genotype is the most common (Strzalkowska et al, 2002;Neamt et al, 2017). On the other hand, Bartoňová et al (2012) found out that the most frequent genotype in Czech Simmental cattle was the AB genotype (0.487), followed by the AA (0.296) and BB (0.156) genotypes.…”

“…CSN3, CSN2 a LGB loci have been the most examined in this context. There is a large amount of research demonstrating the influence of the above-mentioned genes on quantitative and qualitative components of milk production and on selected milk quality indicators (Ozdemir et al, 2018;Neamt et al, 2017). On the other hand, however, there are also studies that have not confirmed the aforesaid correlations (Duifhuis-Rivera et al, 2014;Dogru, 2015).…”

Association of polymorphisms in the CSN2, CSN3, LGB and LALBA genes with milk production traits in Holstein cows raised in Turkey

“…Czerniawska-Piatkowska et al (2011) found that cows with the LGB AA genotype were characterized by the highest milk yield in all lactations and cows with the LGB BB genotype was associated with the highest milk fat yield and content for the three lactations. Neamt et al (2017) reported that the AB genotype was associated with a higher milk production and the BB genotype was associated with a higher fat percentage in milk compared with the other two genotypes. Neither did Litwinczuk et al (2003) and Micinski et al (2008) find any association between LGB genotypes and milk production traits.…”