The influence of comorbid personality disorder on the effects of behavioural activation vs. antidepressant medication for major depressive disorder: Results from a randomized trial in Iran

Moradveisi, Latif; Huibers, Marcus J.H.; Renner, Fritz; Arasteh, Modabber; Arntz, Arnoud

doi:10.1016/j.brat.2013.05.006

Cited by 20 publications

(25 citation statements)

References 14 publications

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“…Contrary to what is often assumed, no adverse effects of PD (features) on treatment retention in both CT and IPT were found. This is consistent with most (Fournier et al, 2008;Kool et al, 2003;Sullivan et al, 1994), but not all previous literature: one study reported that PD was associated with higher dropout; however these findings may be somewhat limited, since only a small proportion of the participants had a PD (Moradveisi et al, 2013). Regarding MDD outcome, the current study did not find a (negative) impact of PD on depressive symptom change and remission.…”

Section: Discussionsupporting

confidence: 91%

“…Another concern is that only a few studies provide data on the relationship between PD and dropout (Kool et al, 2005), which can lead to biased or inaccurate conclusions. The few studies that reported drop-out rates have mixed results: some showed no difference between individuals with and without PD (Fournier et al, 2008;Kool et al, 2003;Sullivan et al, 1994), while others reported higher drop-out rates for individuals with PD (Moradveisi et al, 2013). In addition, despite substantial differences (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Individuals with major depressive disorder (MDD) often meet criteria for DSM defined co-morbid personality disorders (PD), in particular PD's grouped in cluster C: obsessive compulsive PD, dependent PD and avoidant PD (Friborg et al, 2014). Despite extensive research spanning several decades, results from research into the impact of comorbid PD on the effectiveness of acute phase treatment for MDD is equivocal; results vary from a negative association between the presence of a co-morbid PD and clinical outcome (Hardy et al, 1995;Newton-Howes et al, 2014;Reich and Vasile, 1993;Sato et al, 1994) to the absence of any difference between outcome in individuals with and without co-morbid PD (De Bolle et al, 2011;Kool et al, 2005;Moradveisi et al, 2013;Mulder, 2002). These inconsistencies across studies are probably best explained by methodological problems.…”

Section: Introductionmentioning

confidence: 99%

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The impact of personality disorder pathology on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder

Bronswijk

Lemmens

Viechtbauer

et al. 2018

Journal of Affective Disorders

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The impact of personality disorder pathology on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder

Bronswijk

Lemmens

Viechtbauer

et al. 2018

Journal of Affective Disorders

Self Cite

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“…Therefore, the presence, chronicity, and severity of marked maladaptive personality traits together comprise yet another important variable influencing the efficacy of ADT in MDD, one often indicative in the practice of treatment resistance and MDD recurrence. Patients with “Cluster A or Cluster B” personality pathology appear to have less satisfactory results to medication management, whereas those with Cluster C symptoms tend to do better (Wilberg et al ., 1998[47]; Peselow et al ., 1994[31]; Maddux et al ., 2009[24]; and Moradveisi et al ., 2013[27]). It also appears that MDD patients who have suffered trauma or abuse may preferentially respond to PPPT, whereas those without a trauma history appear to do well on an ADT alone (Nemeroff et al ., 2003[28]).…”

Section: Treating Major Depressive Disorder: Predictors Of Patient Rementioning

confidence: 99%

Neural Implications of Psychotherapy, Pharmacotherapy, and Combined Treatment in Major Depressive Disorder

Schwartz

Santarsieri

2016

Mens Sana Monogr

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Numerous clinical trials have been conducted to determine the utility of antidepressant treatment (ADT), psychotherapy, and combined psycho-pharmaco-psychotherapy (PPPT) in treating major depressive disorder (MDD). While all approaches have shown benefit over placebo to varying degrees, the parallel neurophysiological mechanisms that underlie their efficacy have received little attention. The authors will review and discuss a growing body of literature that relates the factors of treatment selection and response to the principles of neuromodulation, with emphasis regarding how neuroimaging and other experimental data reinforce the need for personalized MDD treatment. This manuscript and its theoretical approaches were supported by conducting relevant literature searches of MEDLINE and PubMed electronic databases, prioritizing systemic reviews, and randomized clinical trials using selected MeSH terms. The authors conclude that ADT, psychotherapy, and PPPT all create potentially observable neurofunctional changes and argue that additive and synergistic potentiation of these effects in PPPT may produce more sustained symptom relief than with monotherapy alone.

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“…Therapies under examination were SPSP, 30,31 DBT skills training 42 and IPT. 23 The remaining two studies that compared pharmacotherapy directly with a psychological treatment found BA to be more effective than pharmacotherapy 34 and CT to be less effective than pharmacotherapy. 28…”

Section: Pharmacotherapy Vs Psychological Treatmentsmentioning

confidence: 99%

Psychological treatment of depression and anxiety in patients with co‐morbid personality disorder: A scoping study of trial evidence

French

Turner

Dawson

et al. 2017

Personality & Mental Health

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It is unclear what the best psychological treatment is for depression and anxiety in people with co-morbid personality disorder. Trials of different psychological treatment options for this patient group have been conducted, but this evidence has not previously been systematically reviewed or critically appraised. We set out to conduct a scoping review in order to describe which psychological therapies appear most effective in treating depression and/or anxiety in patients with co-morbid personality disorder. PsycINFO, Cochrane library trials, Medline and Embase databases were searched for studies involving randomized, controlled, experimental, parallel-arm comparisons, examining any well-defined, psychotherapeutic intervention for adults, in an outpatient setting, with a clearly defined diagnosis of depression and/or anxiety, and co-morbid personality disorder. A total of 1662 papers were identified. Fifteen met criteria for inclusion and were reviewed. There was weak evidence to support the use of cognitive behavioural therapy as a psychological treatment for depression in patients with co-morbid personality disorder. However, the literature is characterized by considerable methodological heterogeneity, and further research is needed before there is sufficient evidence to indicate which psychological treatment would be most effective in treating anxiety and/or depression in this patient group. Copyright © 2017 John Wiley & Sons, Ltd.

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The influence of comorbid personality disorder on the effects of behavioural activation vs. antidepressant medication for major depressive disorder: Results from a randomized trial in Iran

Cited by 20 publications

References 14 publications

The impact of personality disorder pathology on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder

The impact of personality disorder pathology on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder

Neural Implications of Psychotherapy, Pharmacotherapy, and Combined Treatment in Major Depressive Disorder

Psychological treatment of depression and anxiety in patients with co‐morbid personality disorder: A scoping study of trial evidence

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