The influence of a hydrogen peroxide and glycerol containing mouthrinse on plaque accumulation: a 3‐day non‐brushing model

Abstract

The results of this pilot study showed that there was no statistically significant difference between the H(2)O(2)/glycerol group and the placebo group with respect to plaque inhibition within this study design.

The effects of hydrogen peroxide mouthwashes on the prevention of plaque and gingival inflammation: a systematic review

“…The manufacturer considered the addition of glycerol sufficient to improve stability and ensured an antiplaque effect. However, the plaque growth inhibiting effect of 0.013% H 2 O 2 combined with 0.004% glycerol was found to be insignificant within the present study design (45).…”

“…(15) also stated that efficacy of H 2 O 2 was not associated with use of H 2 O 2 at <1%. The concentration H 2 O 2 that was used for study # VI (45) was much lower as the above‐mentioned concentrations. The manufacturer considered the addition of glycerol sufficient to improve stability and ensured an antiplaque effect.…”

A Systematic Review of the Effect of Oral Rinsing with H2O2 on Clinical and Microbiological Parameters Related to Plaque, Gingivitis, and Microbes

“…(2) Experimental Gingivitis Studies . Among the studies that evaluated plaque parameters, 3 used the experimental gingivitis model [ 16 , 18 , 22 ]. The information coming from these studies gives an idea of efficacy of the mouth rinses in undisturbed dental biofilms.…”

“…Four of the six studies that allowed oral hygiene compared 1.5% H 2 O 2 with a negative control [ 11 , 15 , 19 , 20 ] and 2 of them with chlorhexidine [ 12 , 21 ], and one of them was also compared to a negative control [ 12 ]. Among the studies that used the experimental gingivitis model [ 16 , 18 , 22 ], two were compared with a negative control [ 18 , 22 ] and the other included a positive control [ 16 ]. In one study, the effect of H 2 O 2 was compared to chlorhexidine, but it was not possible to determine if mechanical plaque control was allowed [ 10 ].…”

Efficacy of probiotics used as a periodontal treatment aid: A pilot study

“…Chlorhexidine has been shown to disrupt supragingival plaque (Gupta et al, 2014, James et al, 2017). Previous studies have not found consistent decrease of dental plaque accumulation by hydrogen peroxide (Hoenderdos et al, 2009, Hossainian et al, 2011); however, probiotics can affect the concentration of collagenolytic molecules in saliva which may contribute to the reduction of plaque accumulation (Jäsberg et al, 2018). This may partially explain the highly significant decrease in plaque accumulation observed in our sample using the probiotic mouthwash.…”