The effects of hydrogen peroxide mouthwashes on the prevention of plaque and gingival inflammation: a systematic review

Hossainian, N; Slot, DE; Afennich, F; Weijden, GA Van der

doi:10.1111/j.1601-5037.2010.00492.x

Cited by 43 publications

(47 citation statements)

References 56 publications

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“…23,24,26 Five studies compared active ingredients, of which 2 also contributed data for the singles active ingredients. 27,28 In one publication, a combination of 2 active ingredients was systematically evaluated. 29 …”

Section: Quality Assessmentmentioning

confidence: 99%

Can Chemical Mouthwash Agents Achieve Plaque/Gingivitis Control?

Weijden

Sluijs

Ciancio

et al. 2015

Dental Clinics of North America

104

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Also note that structured abstracts are not allowed per journal style: What is the effect of a mouthwash containing various active chemical ingredients on plaque control and managing gingivitis in adults based on evidence gathered from existing systematic reviews? The summarized evidence suggests that mouthwashes containing chlorhexidine(CHX) and essential oils (EO) had a large effect supported by a strong body of evidence. Also there was strong evidence for a moderate effect of cetylpyridinium chloride(CPC). Evidence suggests that a CHX mouthwash is the first choice, the most reliable alternative is EO. No difference between CHX and EO with respect to gingivitis was observed.

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Section: Quality Assessmentmentioning

confidence: 99%

Can Chemical Mouthwash Agents Achieve Plaque/Gingivitis Control?

Weijden

Sluijs

Ciancio

et al. 2015

Dental Clinics of North America

104

View full text Add to dashboard Cite

show abstract

“…However, for most commercially available mouthwashes, the scientific evidence is considered to be moderate, weak, or underreported. For instance, the underlying data retrieved in a systematic review for oxygenating agents (OAs) did not allow for a meta-analysis [5]. …”

Section: Introductionmentioning

confidence: 99%

“…Oxygenating agents, such as hydrogen peroxide (H 2 O 2 ), buffered sodium peroxyborate, and peroxycarbonate, have been recommended for short-term use as disinfectants [4, 5]. Recently a mouthwash containing an oxygenating agent (peroxoborate) has been introduced in the market and the result of a pilot study has shown that this product has the potential for selective inhibition of oral bacteria.…”

Section: Introductionmentioning

confidence: 99%

Effect of mouthwashes on the composition and metabolic activity of oral biofilms grown in vitro

et al. 2016

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ObjectiveThe aim of this study was to determine the effect of an oxygenating mouthwash compared to two other established mouthwash products on bacterial composition and metabolic activity of oral biofilms in vitro.Material and methodsTwelve healthy subjects participated as donors. Plaque-saliva mixture inoculated biofilms were grown and treated with 3 different chemotherapeutic mouthwashes [amine fluoride/stannous fluoride (MD), oxygenating agent (AX), chlorhexidine 0.12 % (PA), and water (W)]. Effects of treatments were assessed on biofilm composition (16S rRNA gene amplicon sequencing), production of organic acids (formate, acetate, lactate, propionate, butyrate using capillary electrophoresis), and viability of the remaining biofilm (CFUs).ResultsMicrobial profiles of biofilms clustered per inoculum donor and were dominated by the genera Veillonella, Streptococcus, and Prevotella. Microbial diversity was only reduced after PA treatment. Significant changes in composition occurred after treatment with AX, resulting in lower proportions of Veillonella and higher proportions of non-mutans streptococci. Production of all organic acids after PA and lactate after MD was significantly lower as compared to W. AX resulted in reduction of acetate, butyrate, and propionate and increase in lactate production (p < 0.05). Viable counts were significantly lower after PA and AX treatments compared to W, while no significant reduction was observed after MD.ConclusionsAll studied mouthwashes affected the in vitro biofilms differently. The effects of the AX treatment were the most prominent which resulted in changes of the bacterial composition and metabolism.Clinical implicationsAwareness by the dental team that mouthwashes can change the bacterial composition and metabolism is important when advising its use.

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“…The use of chemical plaque control agents to control plaque and gingivitis levels has been widely evaluated and efficacy for some formulations has been observed in different systematic reviews. [2][3][4][5][6][7][8][9][10] Out of a number of chemical plaque control agents available, chlorhexidine is considered as a gold standard. 11 Though it obeys many features of the ideal chemical agent for plaque control, there are many limitations regarding the safety of its usage over extended periods.…”

Section: Introductionmentioning

confidence: 99%