“…Agglutinins in this man developed late, but ultimately were in high titre, and it is recognized that a delay of weeks or months may occur even in the normal individual-indeed, that the whole process may pass without any detectable agglutinins being formed at all (Evans, 1934). Hardy et al (1938), studying cases diagnosed in New York whose onset can be accurately dated because the entire milk supply to the city is pasteuriied and infection by this means can result only from visits outside the Metropolitan area, stress the. insidiousness of onset of the disease and the uncertainty regarding the early symptoms in the patient's own mind.…”