Brucellosis as a Hazard of Blood Transfusion

Wood, Eileen E.

doi:10.1136/bmj.1.4904.27

Cited by 51 publications

(21 citation statements)

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“…Human-to-human transmission is uncommon but it has been described after blood transfusion [8], bone marrow transplantation [9] and possibly during sexual intercourse [10]. Brucellosis is common in the Mediterranean region, East Africa, Arabian Gulf region.…”

Section: Introductionmentioning

confidence: 99%

The effects of maternal brucellosis on pregnancy outcome

Elshamy

Ahmed²

2008

J Infect Dev Ctries

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Background: Our aim was to assess the outcome of pregnancies complicated by Brucella infection. Design: Prospective study. Setting: EL-Hasan National Hospital, El-Rawad Clinic, TAIF, SAUDI ARABIA (where the practical part of the study was accomplished) and Obstetrics & Gynecology Department, Mansoura University Hospital (where the theoretical part of the study was completed). Methods: This study was conducted from August 2005 to December 2007. Tube method for detection of antibody titre for brucellosis was performed on 450 pregnant women; 415 had no symptoms or signs of brucellosis and 35 had symptoms and signs of the disease.The antibody titre was positive in 55 pregnant women (group 1) and negative in 395 pregnant women (group 2). Both groups were followed up during pregnancy and the neonatal period to determine any type of reproductive failure. Results: The incidence of brucellosis was 12 .2 % among pregnant women included in the study. The incidence of abortion in group I was 27.27%; IUFD was 12. 72%; and preterm labour was 10.90%. There were statistically significant differences in the abortion and IUFD rates but no significant difference in the preterm labour rates between the test and control groups. There was a statistically significant difference in abortion rates between patients with a titre more than 1/160 and those with a titre less than 1/160 (p=0.03). Conclusion: The frequency of fetal loss among patients with brucellosis is very high. It is advisable to have a high degree of alertness for brucellosis in endemic areas.

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Section: Introductionmentioning

confidence: 99%

The effects of maternal brucellosis on pregnancy outcome

Elshamy

Ahmed²

2008

J Infect Dev Ctries

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“…Treatment of both mother and the neonate with rifampicin and trimethoprim/sulfamethoxazole effectively treated brucellosis without any complications. Combination of rifampicin and trimethoprim sulfa for treatment of brucellosis with favorable outcome has also been reported previously [2][3]21].…”

Section: Discussionmentioning

confidence: 91%

“…Although human-to-human transmission is rare, vertical transmission from mother to baby during pregnancy has been reported [2]. Other modes of human-to-human transmission of brucellosis include blood transfusion [1,3], transplantation [4], and breastfeeding [5].…”

Section: Introductionmentioning

confidence: 99%

Neonatal brucellosis: A case report

Alnemri

Hadid

Hussain

et al. 2017

J Infect Dev Ctries

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“…1,2 However, person-to-person transmission has been reported. [3][4][5][6][7] Brucella melitensis infection is well documented in childhood, [8][9][10][11][12][13][14][15] but neonatal infection is rare. [16][17][18][19][20][21][22][23] Blood transfusion-related transmission has been reported in two adults and two thalassaemic children.…”

Section: Introductionmentioning

confidence: 99%

Neonatal brucellosis and blood transfusion: case report and review of the literature

Al-Kharfy

2001

Annals of Tropical Paediatrics

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Neonatal brucellosis following blood transfusion has not previously been reported. A premature male infant born at 24 weeks gestation developed low grade fever and decreased activity and showed poor weight gain at 45 weeks post-menstrual age. Blood culture grew Brucella melitensis and the brucella antibody titre was positive. He received a 6-week course of septrin and rifampicin and made a full recovery. The infant had received a blood transfusion 5 days prior to his illness. The blood donor had symptoms suggestive of brucellosis, and it was suspected that the blood transfusion was the source of infection but this could not be confirmed as the donor was not traceable. It is suggested that, in areas endemic for brucellosis, prospective blood donors should be questioned about symptoms of brucellosis, and serological tests to screen for brucellosis might be indicated.

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Brucellosis as a Hazard of Blood Transfusion

Cited by 51 publications

References 1 publication

The effects of maternal brucellosis on pregnancy outcome

The effects of maternal brucellosis on pregnancy outcome

Neonatal brucellosis: A case report

Neonatal brucellosis and blood transfusion: case report and review of the literature

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