The incidence of vitamin D deficiency in the obese: a retrospective chart review

Daniel, Deepu; Hardigan, Patrick C.; Bray, Natasha; Penzell, Dennis H.; Savu, Christina

doi:10.3402/jchimp.v5.26069

Cited by 25 publications

(13 citation statements)

References 10 publications

(11 reference statements)

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“…Also, being fat‐soluble, more vitamin D may be sequestered in the abdominal fat, hence lowering circulating vitamin D . Vitamin D deficiency has been confirmed in obese subjects . In African–American overweight and obese subjects, supplementation with vitamin D (1,000, 2,000 and 4,000 IU) did not alter the body weight or the BMI in 6 months even though the plasma vitamin D was increased .…”

Section: Vitaminsmentioning

confidence: 99%

Functional foods as potential therapeutic options for metabolic syndrome

2015

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Obesity as part of metabolic syndrome is a major lifestyle disorder throughout the world. Current drug treatments for obesity produce small and usually unsustainable decreases in body weight with the risk of major adverse effects. Surgery has been the only treatment producing successful long-term weight loss. As a different but complementary approach, lifestyle modification including the use of functional foods could produce a reliable decrease in obesity with decreased comorbidities. Functional foods may include fruits such as berries, vegetables, fibre-enriched grains and beverages such as tea and coffee. Although health improvements continue to be reported for these functional foods in rodent studies, further evidence showing the translation of these results into humans is required. Thus, the concept that these fruits and vegetables will act as functional foods in humans to reduce obesity and thereby improve health remains intuitive and possible rather than proven.

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Section: Vitaminsmentioning

confidence: 99%

Functional foods as potential therapeutic options for metabolic syndrome

2015

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“…reported a strong negative correlation between BMI and 25(OH)D level. Previous studies have reported that BMI declined when serum 25(OH)D levels were corrected from deficiency status . Interestingly, Vimaleswaran et al .…”

Section: Discussionmentioning

confidence: 97%

Serum level of 25‐hydroxyvitamin D and obesity among early pregnant women

Mahmoud

Saad

Mohieldein

et al. 2019

J of Obstet and Gynaecol

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Aim: To assess serum 25-hydroxyvitamin D 25(OH)D level in obese pregnant Sudanese women in early pregnancy. Methods: A match case-control study was conducted in Saad Abualila Hospital (Khartoum, Sudan). The cases were obese (body mass index [BMI] ≥ 30.0 kg/m 2 ) women. Controls were women with normal BMI (18.5-24.9 kg/m 2 ) matched for age, parity and gestational age. The 25(OH)D level was measured using ELISA.Results: There was no significant difference between the two groups in their age, parity or gestational age. There was no significant difference in the median (interquartile) level of the serum (25(OH)D between obese pregnant women and normal weight pregnant women (3.05 [11.100-15.937] ng/ml vs 13.05 [10.950-17.362] ng/ml, P = 0.237). There was no significant correlation between BMI and 25(OH)D level (r = −0.133, P = 0.149). Conclusion: There was no significant difference in the 25(OH)D level between the obese pregnant women and normal weight pregnant women in this study.

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“…Probably, the active form of vitamin D decreases expression of pro-inflammatory cytokines such as IL-6, IL-1, and TNF-α involved in insulin resistance [149]. Some studies report a negative relationship between serum 25(OH) D levels, BMI [150][151][152], and HOMA-IR [147,152]. Maternal overweight and obesity are among the highest modifiable risk factors.…”

Section: Interaction Between Iron and Adipocytesmentioning

confidence: 99%

Body Mass Index and Insulin Sensitivity/Resistance: Cross Talks in Gestational Diabetes, Normal Pregnancy and Beyond

Genova¹,

Atanasova²,

Todorova-Ananieva³

2019

Body-Mass Index and Health

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Pregnancy is a complex of metabolic, physiological, biochemical, and immunological changes in women's body, usually reversible after delivery in normal pregnancy. Gestational diabetes mellitus (GDM) is defined as "any degree of glucose intolerance with onset or first recognition during the current pregnancy." The etiology of the GDM is multifactorial and not sufficiently elucidated. The overweight and obesity during prepregnancy and pregnancy are one of the main modifiable risk factors of GDM. Maternal obesity increases the risk of a number of pregnancy complications, adverse pregnancy outcome for mother and child, and related chronic conditions in women. The obesity prevalence is the greatest among children of obese mothers, and an independent association between maternal body mass index and offspring adiposity and insulin resistance exists. Although the underlying mechanism remains unclear, available evidence suggests that GDM pathogenesis is based on relatively diminished insulin secretion coupled with pregnancy-induced insulin resistance. Recent findings provide data that higher BMI leads to decreased insulin sensitivity and higher degree of insulin resistance and contributes to GDM development.

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The incidence of vitamin D deficiency in the obese: a retrospective chart review

Cited by 25 publications

References 10 publications

Functional foods as potential therapeutic options for metabolic syndrome

Functional foods as potential therapeutic options for metabolic syndrome

Serum level of 25‐hydroxyvitamin D and obesity among early pregnant women

Body Mass Index and Insulin Sensitivity/Resistance: Cross Talks in Gestational Diabetes, Normal Pregnancy and Beyond

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