The incidence of cervical intraepithelial neoplasia in antenatal women by screening: a study in a semi urban area in Telangana, India

Abstract

Background: Cervical intraepithelial neoplasia is a premalignant cervical disease which may lead to cervical cancer. The screening of the cervical cancer includes the screening of cervical cytology as well as testing for oncogenic human papilloma viruses (HPV) since most of the precursor lesions appear in the women of child bearing age. The purpose of the present study was to evaluate the incidence of cervical intraepithelial neoplasia in antenatal women by screening with papanicolaou smear.Methods: Macroscopic abnormalities such as cervicitis, polyps, erosions, nabothian cysts, hypertrophied cervix, growths and ulcers were noted. A cervical smear using Ayre’s spatula was taken from the ecto cervix and spread on to a labeled slide and immediately fixed.Results: Majority of the women were in the age group of 20-30 years in the study group. The overall mean age of the women in the study was around 25 years. The mean age at the time of menarche was around 14 years and at the time of marriage was approximately 22 years. On Pap smear, 55.2% of the 1000 cases were normal, with inflammation seen in 408 (40.8%) of the cases. 20 (2%) of the patients in our study had low grade squamous intra epithelial lesion, while 7 patients (0.2%) had high grade squamous intra epithelial lesion with two cases showing CIN II grading and 5 with CIN I.Conclusions: An early detection of the same can lead to a proper and efficient treatment.

Cervical Cytology and its Correlation with Cervicovaginal Infection in Antenatal Patients: A Study in a Tertiary Care Hospital

“…In our study, mean age of the cases is 11 Neelima et al also found the overall mean age of the women in the study was around 25 years. 12 A study conducted by Khaengkhor et al where the majority of women, i.e., 50.3% were primigravidae as compared to multigravidae in 49.7% which is consistent with our study. 11 A cross-sectional study conducted by Ingprasarn et al on 472 antenatal women in which maximum number (50%) of women were primigravidae.…”

“…16 Neelima et al conducted a study on 1000 antenatal women, on Pap smear 55.2% cases were normal, with inflammation seen in 40.8% cases and dysplasia was seen in two women, which is consistent with our study. 12 On wet mount, 78.2% were showing pus cells on Normal saline, and fishy odor on KOH suggestive of Bacterial vaginosis followed by 19.4% cases were showing budding yeast cells on both normal saline and KOH suggestive of vaginal candidiasis followed by only 2.4% were showing trophozoites on wet mount suggestive of trichomoniasis. A study conducted by Govender et al found bacterial vaginosis in 52% of the women and was the most common infection diagnosed.…”