“…201 CT can quantify the extent of inflammatory disease based upon opacification of the paranasal sinuses; 198 however, patient symptoms and quality of life do not necessarily correlate with the extent of disease seen on CT. 19,20,141 Allergy and Immunology Evaluation: Evidence supports the association of allergy and rhinosinusitis in adults. 159,[202][203][204][205][206] Most patients with extensive sinus disease, quantified by CT, have demonstrated evidence of allergy, 165,207 and about twice as many patients with allergic rhinitis, compared with normal subjects, have abnormal CT scans (67% vs 33%). 208 Identification of allergies, however, does not imply they are the only cause of sinusitis, and other factors should be considered.…”