The Impact of allergic and nonallergic rhinitis on pediatric sinusitis

Abstract

There is a great deal of published evidence that there is a relationship between both allergic and nonallergic rhinitis and sinusitis in both pediatric and adult patients. The relationship between rhinitis and sinusitis may involve inflammation in one compartment leading to secondary inflammation in the other compartment, such as in the case of rhinitis leading to obstruction of the osteomeatal complex. The relationship may also involve individual manifestations of a shared process, such as allergic disease. A better understanding of the relationship between rhinitis and sinusitis may significantly influence the treatment of these common and important conditions.

Comorbidity has no impact on eosinophil inflammation in the upper airways or on severity of the sinonasal disease in patients with nasal polyps

“…Therefore, the contribution of allergy to the total inflammatory picture in CRS is debatable. In contrast to our results, other studies have shown that atopic patients suffer from more severe CRS . Negative effect of allergy on treatment outcome was also reported …”

The role of antibiotics in pediatric chronic rhinosinusitis

“…PCRS can also occur and/or be aggravated by allergic rhinitis and adenoid disease. 4,5 The factors that may enhance the development of CRS include anatomical blockage, exposure to allergens and irritants, defects in mucociliary function, immunodeficiency, and bacterial, viral, and fungal infection. The frequent end result of these is local inflammation and swelling of the sinonasal mucosa leading to impairment of normal sinus drainage and secondary bacterial infections.…”

Seasonal Allergic Rhinitis

“…Allergic rhinitis may lead to nasal congestion and swelling of the membrane of the nasal mucosa which may, in turn, obstruct normal sinus drainage through osteomeatal complex [23]. There is also the possibility that inflammation in the nose and sinuses can be part of the allergic disease [23].…”

“…There is also the possibility that inflammation in the nose and sinuses can be part of the allergic disease [23]. Patients with allergic rhinitis are therefore at increased risk for sinusitis [7].…”

“…These preparations have a faster onset of action than is generally appreciated [23]. Once-daily dosing is possible with most medications in this class [42,56].…”