The Improvement Effects of β-Glucan on Adiposity and Serum Lipids Levels in High Fat Diet-Induced Obese Rats

홍경희,; 김현순,; 장기효,; 강순아,

doi:10.5762/kais.2015.16.6.3973

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…Studies preparing or treating obesity are actively in progress including clinical trials mainly conducted on mice and rats to analyze the effect of food, medications, and exercise on obesity. In most of these studies, the degree of increase in actual fat weight was estimated with the fat tissue extracted by dissecting experiment [2–5]. Dissection experiment (EXP) method of a euthanized animal can be relatively accurate compared with the noninvasive methods.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of iNSiGHT VET DXA (Dual-Energy X-ray Absorptiometry) for assessing body composition in obese rats fed with high fat diet: a follow-up study of diet induced obesity model for 8 weeks

Yeu

Kim

et al. 2019

Lab Anim Res

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We examined the precision, accuracy, and capability of detecting changes of Dual-Energy X-ray Absorptiometry (DXA) for the measurements of total-body weight (TBW), total-body fat weight (TBFW), and total-body lean weight (TBLW) in an 8-week follow-up study of rats. Twenty male rats (4-week) were divided into 2 diet groups. For 8 weeks, we measured body composition (TBW, TBFW, TBLW) by DXA and TBW by an electronic scale once a week. In week 8, we measured body composition 5 times by DXA and TBFW by dissecting experiment (EXP) of euthanized rats (12-week). Total-body fat ratio (TBFR) was defined as TBFW/(TBFW+TBLW). The precision of DXA was evaluated by measuring the coefficient of variation (CV) and accuracy was evaluated by comparing DXA-derived data with EXP data. The capability of detecting changes of DXA in follow-up study was verified by analyzing the trend of DXA-derived values over the 8 weeks. For TBW, TBFW, TBLW of DXA, CVs were 0.02 ± 0.01, 0.10 ± 0.05, 0.03 ± 0.02 and errors were − 6.996 ± 3.429 ( r = 0.999), + 14.729 ± 3.663 ( r = 0.982), − 21.725 ± 4.223 ( r = 0.991), respectively. Prediction models were [EXP TBW = − 31.767 + 1.085 (DXA TBW), R2 = 0.998, root mean square error (RMSE) = 1.842] and [EXP TBFR = − 0.056 + 1.177 (DXA TBFR), R2 = 0.948, RMSE = 0.007]. Over 8 weeks, DXA TBW and DXA TBLW steadily increased, DXA TBFW steadily increased followed by saturation or declination, difference of DXA TBFW between 2 diet groups steadily increased. In conclusion, our study verified that DXA (iNSiGHT VET DXA, OsteoSys, Korea) is accurate and precise enough to measure body composition of rats. Additionally, we confirmed the possibility that DXA could be used for the long-term follow-up studies.

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Section: Introductionmentioning

confidence: 99%

Evaluation of iNSiGHT VET DXA (Dual-Energy X-ray Absorptiometry) for assessing body composition in obese rats fed with high fat diet: a follow-up study of diet induced obesity model for 8 weeks

Yeu

Kim

et al. 2019

Lab Anim Res

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“…버섯의 다양한 생리활성 물질이 밝혀져 있다. 버섯의 기능성 물 질 중 베타글루칸은 다당류의 일종으로 버섯류, 효모, 곡류 등 에 존재하고 있는데 [7], 수용성 식이섬유인 베타글루칸이 우리 몸으로 들어오면 혈액으로 흡수돼 암 세포 등을 잡아먹는 대식 세포를 활성화시키며 [8], 지질 대사 개선을 유도하고 체지방 형 성과 축적을 억제한다 [9]. 또, 베타글루칸은 면역증진 및 항암 활성이 있다 [10].…”

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Effect of Lentinula edodes water extracts and Lentinan on proliferation of myosatellite cell of Bos taurus Hanwoo

Kim

Park

et al. 2023

JABC

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Effects of Dietary DFA IV on Lumen Short Chain Fatty Acids Production and Intestinal Environment in Rats

Hong¹,

Jang²,

Kang³

2016

Journal of the Korea Academia-Industrial cooperation Society

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The Improvement Effects of β-Glucan on Adiposity and Serum Lipids Levels in High Fat Diet-Induced Obese Rats

Cited by 3 publications

References 33 publications

Evaluation of iNSiGHT VET DXA (Dual-Energy X-ray Absorptiometry) for assessing body composition in obese rats fed with high fat diet: a follow-up study of diet induced obesity model for 8 weeks

Evaluation of iNSiGHT VET DXA (Dual-Energy X-ray Absorptiometry) for assessing body composition in obese rats fed with high fat diet: a follow-up study of diet induced obesity model for 8 weeks

Effect of Lentinula edodes water extracts and Lentinan on proliferation of myosatellite cell of Bos taurus Hanwoo

Effects of Dietary DFA IV on Lumen Short Chain Fatty Acids Production and Intestinal Environment in Rats

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