In this study, a postural change detection sensor module (PCDSM) was developed to detect postural changes in activities of daily living (ADL) and falls. The PCDSM consists of eight mercury sensors that measure angle variations in 360° rotation and 90° tilting. From the preliminary study, the output characteristics of the PCDSM were confirmed with the angle variations of rotational motion and a tilting table. Three experiments were conducted to test rotational motion, postural changes, and falling and lying. The results confirmed that the PCDSM could effectively detect postural changes, movement patterns, and falls or non-falls.