The Importance of a High-Pitched Squeaking Systolic Murmur in the Diagnosis of Aortic Stenosis and Calcification of the Aortic Valve

Braun, H; Comeau, Wilfrid J.

doi:10.1056/nejm195104052441403

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Pathophysiology and Diagnosis1

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1952

2014

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Cited by 7 publications

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“…Peaking of the murmur late in systole, a palpable delay of the carotid upstroke, and a soft second heart sound can all point to aortic stenosis. Aortic stenosis is usually confirmed using ultrasound echocardiography (Nakamura et al, 1984, Braun & Comeau, 1951. The severity of aortic valve dysfunction is determined by the combination of the following hemodynamic indices: peak ejection velocity, effective orifice area, and mean transvalvular pressure gradient (Nakamura et al, 1984).…”

Section: Pathophysiology and Diagnosismentioning

confidence: 99%

Calcific Aortic Valve Disease

2013

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Section: Pathophysiology and Diagnosismentioning

confidence: 99%

Calcific Aortic Valve Disease

2013

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Aortic Stenosis —Clinical Manifestations and Course of the Disease

Bergeron¹

1954

AMA Arch Intern Med

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Aortic Stenosis Manifested as Chronic Cor Pulmonale

Soloff¹,

Zatuchni²,

Turner³

1952

JAMA

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pitalization, one week prior to the onset of tetraethylthiuram disulfide therapy. It was felt that the alcohol content of the robitussin® cough syrup might be responsible for the patient's difficulties, and the discontinuance of this medication resulted in a complete return of the patient to "normal." COMMENT The many reports of "psychotic reactions" to the continued use of tetraethylthiuram disulfide suggest that these reactions are toxic manifestations of treatment with the drug. While this may certainly be so in some cases, the present report suggests that some of these reactions might be due to the concomitant repeated intake of small amounts of "masked" or "unknown" alcohol, in the form of "ordinary" simple medicines or even, perhaps, by percutaneous absorption or inhalation of alcohol during the use of alcoholic preparations and lotions such as aftershave lotion. SUMMARY

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The Importance of a High-Pitched Squeaking Systolic Murmur in the Diagnosis of Aortic Stenosis and Calcification of the Aortic Valve

Cited by 7 publications

References 8 publications

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease

Aortic Stenosis —Clinical Manifestations and Course of the Disease

Aortic Stenosis Manifested as Chronic Cor Pulmonale

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