The implementation of neonatal peritoneal dialysis in a clinical setting

Ünal, Sevim; Bilgin, Leyla; Gündüz, Mehmet; Uncu, Nermin; Azılı, Müjdem Nur; Tiryaki, Tuğrul

doi:10.3109/14767058.2012.665105

Cited by 20 publications

(25 citation statements)

References 21 publications

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“…If appropriate, catheter selection and technique in the placement should be done, PD might improve outcome as in the presented case. [2][3][4][5] Now she is alive and on regular outpatient clinic visits for PA. PD, although invasive, is an effective therapy in neonates with the diagnosis of PA and as an emergency tool, PD has been also used in the treatment of metabolic crisis resulting from organic acidemias. 2 …”

Section: Discussionmentioning

confidence: 99%

“…This is particularly important in patients with ammonia 4500 mg/dL, extreme acidosis/ electrolyte imbalance, coma, dilated pupils, poor neurological finding, deterioration, failure to improve. 2 Neonatal-onset PA, the most common form, is characterized by poor feeding, vomiting, and somnolence in the first days of life in a previously healthy infant, followed by lethargy, seizures, coma, and death. It is frequently accompanied by metabolic acidosis with anion gap, ketonuria, hypoglycemia, hyperammonemia, and cytopenias.…”

Section: Discussionmentioning

confidence: 99%

“…Individuals with PA develop worsening metabolic acidosis in the presence of physiological stress from increased catabolism. 2 Herein, we report a case of 3-day-old neonate with PA presented with acute renal failure (ARF) and metabolic acidosis was effectively treated by peritoneal dialysis and conventional methods.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Severe renal failure and hyperammonemia in a newborn with propionic acidemia: effects of treatment on the clinical course

Kasapkara¹,

Akar²,

Yıldırım³

et al. 2013

Renal Failure

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Severe renal failure and hyperammonemia in a newborn with propionic acidemia: effects of treatment on the clinical course

Kasapkara¹,

Akar²,

Yıldırım³

et al. 2013

Renal Failure

View full text Add to dashboard Cite

“…90 If peritoneal dialysis is felt to be a short-term requirement, a temporary catheter can be placed. Several studies describe successful peritoneal dialysis by several different techniques in critically ill neonates as small as 830 g. [91][92][93][94][95] When PD is technically difficult because of abdominal wall defects, skin infections, communication to the pleural space, or high ultrafiltration needs, CRRT can be performed. CRRT is performed with a hemodialysis catheter placed in a central location and either regional or systemic anticoagulation.…”

Section: Neonatal Cardiac Surgerymentioning

confidence: 99%

Neonatal Acute Kidney Injury

et al. 2015

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In recent years, there have been significant advancements in our understanding of acute kidney injury (AKI) and its impact on outcomes across medicine. Research based on single-center cohorts suggests that neonatal AKI is very common and associated with poor outcomes. In this state-of-the-art review on neonatal AKI, we highlight the unique aspects of neonatal renal physiology, definition, risk factors, epidemiology, outcomes, evaluation, and management of AKI in neonates. The changes in renal function with gestational and chronologic age are described. We put forth and describe the neonatal modified Kidney Diseases: Improving Global Outcomes AKI criteria and provide the rationale for its use as the standardized definition of neonatal AKI. We discuss risk factors for neonatal AKI and suggest which patient populations may warrant closer surveillance, including neonates ,1500 g, infants who experience perinatal asphyxia, near term/ term infants with low Apgar scores, those treated with extracorporeal membrane oxygenation, and those requiring cardiac surgery. We provide recommendations for the evaluation and treatment of these patients, including medications and renal replacement therapies. We discuss the need for long-term follow-up of neonates with AKI to identify those children who will go on to develop chronic kidney disease. This review highlights the deficits in our understanding of neonatal AKI that require further investigation. In an effort to begin to address these needs, the Neonatal Kidney Collaborative was formed in 2014 with the goal of better understanding neonatal AKI, beginning to answer critical questions, and improving outcomes in these vulnerable populations.

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“…Periton diyalizi hemodiyalize göre daha kolay, yatak başı uygulanan bir yöntem olup ekstrakorporeal dolaşım olmadığından vasküler kateter ve antikoagülan uygulama gerekliliği yoktur 9 . Etkinliğinin tam olarak belirlenememesi, düşük ultrafiltrasyon hızı, periton sıvısının neden olduğu solunum güçlüğü, sıvı elektrolit dengesizliği ve enfeksiyon riski dezavantaj olmasına rağmen periton diyalizi bugün için DMH tedavisindeki yerini korumaktadır.…”

Section: Periton Diyaliziunclassified

Doğuştan Metabolik Hastalıkların Tedavisinde Ekstrakorporeal Yöntemler

Tolunay¹,

Yildizdaş²,

Horoz³

et al. 2015

Arşiv Kaynak Tarama Dergisi

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Inborn errors of metabolism are hereditary disorders that are related to the accumulation of toxic substances or deficiency of proteins because of enzymatic blokage in the metabolic pathways. Treatment should be quick and aggressive as inborn errors of metabolism might lead to organ damage and even death. This article discusses extracorporeal methods like exchange transfusion, peritoneal dialysis, hemodialysis, plasmapheresis and extracorporeal membran oxygenation for acute management of inborn errors of metabolism apart from medical therapies. Key words: Extracorporeal treatments, inborn errors of metabolism, pediatric intensive care unit. ÖZETDoğuştan metabolik hastalıklar, metabolik yollarda kesinti sonucu kesintinin ardında biriken maddelere veya son ürünün yapılamamasına bağlı bir grup kalıtsal hastalıktır. Doğuştan metabolik hastalıklar organ hasarı, sekel, hatta ölümle sonuçlanabilecek durumlara yol açabildiğinden tedavide hızlı ve agresif davranmak gereklidir. Bu yazıda medikal tedaviler dışında kan değişimi, periton diyalizi, hemodiyaliz, plazmaferez, ekstrakorporeal membran oksijenasyon gibi ekstrakorporeal tedavi yöntemleri tartışılacaktır. Anahtar kelimeler: Doğuştan metabolik hastalık, ekstrakorporeal tedavi yöntemleri, çocuk yoğun bakım ünitesi.

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The implementation of neonatal peritoneal dialysis in a clinical setting

Abstract: PD, although invasive, is an effective therapy in neonates. The complexity and invasiveness of the procedure is probably responsible for high rate of complications and mortality. If appropriate catheter selection and technique in the placement should be done, PD might improve outcome.

Cited by 20 publications

References 21 publications

Severe renal failure and hyperammonemia in a newborn with propionic acidemia: effects of treatment on the clinical course

Severe renal failure and hyperammonemia in a newborn with propionic acidemia: effects of treatment on the clinical course

Neonatal Acute Kidney Injury

Doğuştan Metabolik Hastalıkların Tedavisinde Ekstrakorporeal Yöntemler

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