The Impact of the Method of Prevention of Intrauterine Infection on the State of Nonspecific Immunity in Pregnant Women With Relapsing Herpetic Infection and Their Children

Ovchinnikova, M. A.; Липатов, И. С.; Санталова, Г. В.; Tezikov, Yu. V.

doi:10.22625/2072-6732-2018-10-1-70-79

Cited by 2 publications

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“…Despite the improvement of the basic parameters which characterize the specific weight of infections (Sukhanova and Sklyar, 2007) in the structure of perinatal and gynecological morbidity (Orekhov, 2002;Volodin, 2001), herpes infection remains the main cause of neonatal morbidity and mortality (Lutoshin, 2005;Subramaniam and Britt, 2018). Herpes virus infections are opportunistic infections, when a virus can exist for a long time in the human body, it may not reveal itself and cause any pathological phenomena, but when the body protective functions decrease, the virus begins to multiply intensely and impair various organs and systems (Ovchinnikova et al, 2018).…”

Section: аннотацияmentioning

confidence: 99%

Clinical and Immunological Aspects of Newborn Adaptation Born From Mothers With Intrauterine Infection

Жумалина¹,

Тусупкалиев²,

Zame³

et al. 2020

PTQ

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Today about 40 % of babies are infected with intrauterine infections. The immune statuses of children during the neonatal period are largely associated with the patterns of pregnancies in their mothers. This work aimed to study clinical and immunological features in newborns of mothers with intrauterine infection. 48 infants were observed. Neonates were divided into two groups: group 1 – 33 newborns from mothers infected with cytomegalovirus infection, group 2 – 15 children from healthy mothers. The diagnosis of intrauterine infection verifizierung the basis of survey questionnaire for pregnant women, outpatient data of pregnant women and neonates, serologic study, PCR, ELISA, and the cellular immunity and humoral immunity. Somatic and obstetric and gynecological history of mothers was thoroughly collected and the risk factors for the development of complications in the early period of adaptation were assessed. The result of the study revealed that the structure of risk factors in pregnant women with intrauterine infections is of great importance the age of 30 years, genital and extragenital pathology during pregnancy, spontaneous abortions and non-developing pregnancy, abortion. Associated viral infections (CMV, Cytomegalovirus) predominate in the structure of congenital infection. The analysis indicates significantly burdened perinatal anamnesis in children infectious factors and factors of perinatal hypoxia. The leading clinical symptoms for intrauterine infections among the examined children are in the early neonatal period prematurity asphyxia, urinary symptoms, late neonatal period differ polymorphism symptomatic. In this period reveals a specific organ of the Central nervous system. In newborns with intrauterine infections observed inhibition of immunological indicators (CD4+, Cd8+, Cd 19+).

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Section: аннотацияmentioning

confidence: 99%

Clinical and Immunological Aspects of Newborn Adaptation Born From Mothers With Intrauterine Infection

Жумалина¹,

Тусупкалиев²,

Zame³

et al. 2020

PTQ

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Features of the Course of Perinatal Infections at the Present Stage

Vygivska

Руденко²,

Kalnytska

et al. 2020

Wiad Lek

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The aim: To characterize the course of the most common perinatal infections on the basis of assessment of the literature data. Materials and methods: This article provides an assessment of 125 literature sources submitted to PubMed, Medline, Cochrane Library, CyberLeninka, Google Scholar and V.I. Vernadsky National Library of Ukraine. The description of the most common viral, bacterial and parasitic perinatal infections, transmission methods, clinical manifestations, methods of diagnosis and treatment, their clinical consequences are described. Perinatal infections are the leading cause of severe congenital pathology, a serious worldwide medical and social problem that needs to be addressed. Conclusions: Perinatal infections are a serious issue of today, requiring a multidisciplinary approach and the collaboration of doctors of different specialties. Their prevalence among the population, high rates of perinatal mortality, concealment under the mask of other disorders, and the absence of specific clinical symptoms in pregnant and newborns require careful consideration of this problem. Improving the quality of diagnosis and treatment of this pathological condition will help to minimize the risk of transmission of infection, as well as to avoid a number of abnormaalities in the neonatal period and the development of congenital infection.

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The Impact of the Method of Prevention of Intrauterine Infection on the State of Nonspecific Immunity in Pregnant Women With Relapsing Herpetic Infection and Their Children

Cited by 2 publications

References 0 publications

Clinical and Immunological Aspects of Newborn Adaptation Born From Mothers With Intrauterine Infection

Clinical and Immunological Aspects of Newborn Adaptation Born From Mothers With Intrauterine Infection

Features of the Course of Perinatal Infections at the Present Stage

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