The impact of purple sweet potato water extract on excess weight gain in pregnant mice

Lantika, Uci Ary; Damailia, R.; Bhatara, Tryando; Ekowati, R.R.; Yulianti, A.B.

doi:10.1201/9781003016700-3

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“…In our study, we used both male and female mice to explore the detrimental effects of green tea consumption on pregnancy but in the present research mice of both (control and treated) groups gave births (18 pups) which were devoid of any abnormality. Lantika et al, (2020) and Sarma et al, (2008) found that maternal consumption of green tea extract during pregnancy and lactation did not promote alteration in body weight in mothers and pups as well as intake of green tea extract has no detrimental effects on new-born along with this can promote the reduction rate of retroperitoneal adipose tissue relative weight in 28d-old pups. A high dose of caffeine intake can sometime also affect the bioavailability of folic acid and reduce the serum folic acid levels.…”

Section: Discussionmentioning

confidence: 99%

Excessive Green Tea Intake Alters Hemoglobin (Hb) Concentration and Histoarchitecture of Liver

Kundu

Das

2022

Turkish JAF Sci.Tech.

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A myriad of health claims are being made in favor of the consumption of green tea due to its easy availability and greater popularity. On the contrary, certain health risks of excessive green tea consumption have begun to emerge. The aim of the present research was to observe the baleful effects of excessive green tea intake on hematological parameter and histoarchitecture of liver. A total of thirty (n=30) Swiss albino mice were taken and randomly divided into Control C, Treated T1, and Treated T2 groups. Each group consisted of ten (5 male+5 female) mice. The Control C group was fed with normal mice pellet and water (3ml/mice) orally but the treated T1 group was supplied mice pellet with 2ml/mice of green tea+1ml/mice of water orally as well as treated T2 group was given mice pellet and 3ml/mice of green tea orally two times in a day for 60 days. After the experimental tenure, mice of each group were sacrificed ethically and samples (Blood, liver and lungs) were collected for further hematological and histomorphological studies. Treated T2 group of mice were motionless (inactive and stagnant). Anatomopathologically, the liver surface became dark red in color with considerable hepatomegaly and mild hemorrhage also found on lung surface. Histologically, mild central vein congestion and severe venous congestion with dilation were found in the portal vein of the liver of the treated T2 group of mice. Hematologically, hemoglobin level significantly reduced in the treated T2 group of mice than the others. Within this experimental period, female mice of each group gave birth (15-18 pups) that were devoid of any abnormality. Therefore, it can be concluded that excessive green tea intake in a day might have baleful effects on hematological parameter (Hb concentration) and histoarchitechture of liver in Swiss albino mice.

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Section: Discussionmentioning

confidence: 99%