The Impact of Pharmacist-Based Services Across the Spectrum of Outpatient Heart Failure Therapy

West, Lucianne; Williams, J. Bradley; Faulkenberg, Kathleen D.

doi:10.1007/s11936-019-0750-3

Cited by 8 publications

(13 citation statements)

References 75 publications

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“…DRPs are relatively common in hospital patients and can result in increased patient morbidity and mortality, thus increasing costs [ 2 , 11 ]. From a retrospective review carried out in two hospitals on DRPs among cardiovascular disease (CVD) patients, 58.7% and 41.5% resulted in hospitalization [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Drug-related problems and its predictors among hospitalized heart failure patients at Jimma Medical Center, South West Ethiopia: prospective interventional study

Sefera

Getachew

Babu

et al. 2022

BMC Cardiovasc Disord

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Background Drug-related problems are associated with high mortality, complications, prolonged hospital stay, compromised quality of life, and increased healthcare costs. This problem is high in patients hospitalized with chronic conditions such as heart failure. However, there are limited studies conducted on this area, particularly in Ethiopia. Objective To evaluate drug-related problems, their predictors, and clinical pharmacist intervention among hospitalized heart failure patients at Jimma Medical Center, Ethiopia. Methods and participants A prospective interventional study was conducted among hospitalized heart failure patients from September 30, 2020, to May 28, 2021, at Jimma Medical Center. Drug-related problems were sorted based on the Pharmaceutical Care Network Europe drug classification tool version 9.0. Patient's specific data were collected using a structured questionnaire. Data was analyzed using statistical software package version 23.0. Multivariate logistic regression analysis was used to identify independent predictors of drug-related problems occurrence and statistical significance was considered at a p value < 0.05. Results A total of 237 heart failure patients were included in this study. The mean (SD) age was 49.06 + 17.79. About two-thirds (66.2%) of study patients had at least one drug-related problem during their hospital stay. A total of 283 drug-related problems were identified among 157 patients. Treatment effectiveness-related problem (55.48%) was the most common observed drug-related problem. The independent predictors of drug-related problems were khat chewing [AOR = 3.25, 95% CI = (1.46–7.23)], hospital stay > 18 days [AOR = 3.77, 95% CI = (1.93–7.37)]; presence of comorbid condition [AOR = 2.59, 95% CI = (1.35–4.96)] and polypharmacy [AOR = 2.94, 95% CI = (1.54–5.61)]. Conclusion The prevalence of drug-related problems was high among hospitalized heart failure patients in the study area. Chewing khat, prolonged hospital stay, comorbidity, and polypharmacy were the predictors of drug-related problems. Hence, to overcome these problems, clinical pharmacists, physicians, and other health professionals have to work in collaboration.

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Section: Introductionmentioning

confidence: 99%

Drug-related problems and its predictors among hospitalized heart failure patients at Jimma Medical Center, South West Ethiopia: prospective interventional study

Sefera

Getachew

Babu

et al. 2022

BMC Cardiovasc Disord

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“…This outcome led to fewer HF occurrences and all-cause mortality in the pharmacistmanaged group. 13 These studies demonstrate that pharmacists have an important role in the treatment of chronic conditions beyond medication reconciliation, particularly in the management of HF. As HFpEF guidelines suggest emphasizing treating other HF-related comorbidities, such as blood pressure, pharmacists are equipped to manage pharmacotherapy in patients with multiple chronic cardiac conditions.…”

Section: Discussionmentioning

confidence: 95%

Utilizing Pharmacist-Led Telehealth Services in Ambulatory Patients with Heart Failure

et al. 2023

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Background: Heart failure is one of the leading causes of hospital admissions. Non-adherence to medications and poor dietary management for patients who suffer from this condition can lead to worsening of symptoms and hospitalization. Pharmacist interventions via telehealth have demonstrated a beneficial impact on disease management and adherence outcomes in patients with chronic conditions. Methods: This retrospective, descriptive cohort study reviewed subjects from a single-centered primary care office. Data was collected via electronic chart review between January and December 2021. Subjects eligible for inclusion were adults who were diagnosed with heart failure by their primary care provider and referred to a pharmacist for a telehealth visit. The primary outcome was the number of heart failure-related hospitalizations post-pharmacist intervention via telehealth. The secondary outcome was the number of cardiovascular-related hospitalizations post-pharmacist intervention via telehealth. Results: 37 patients were included for analysis. Only two patients were admitted for heart failure post-pharmacist intervention. Fifteen patients were admitted post-pharmacist intervention for a cardiovascular-related hospitalization. Conclusion: This report illustrates the employment of pharmacist-led telehealth services in the chronic heart failure population. This study encourages pharmacist-based interventions via telehealth in the ambulatory setting as few HF-related hospitalizations occurred in this cohort.

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“…Pharmacist-based services can empower patients with heart failure to understand and manage their complex medication regimens through medication reconciliation, identi cation of drug-drug interactions. In addition, pharmacist-based interventions may improve clinical outcomes, reduce hospital stay, fewer re-admissions and fewer disease events such as HF events or thromboembolism, reuce costs of readmissions and emergency room (17,18).…”

Section: Introductionmentioning

confidence: 99%

Medication Related Problems and its predictors among heart failure patients at a tertiary care hospital in Ethiopia: A prospective interventional study

Garedow

Tesfaye

2023

Preprint

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Background Medication related problems in cardiovascular disease patients, especially among heart failure patients were found to be high. Medication related problem is a critical problem to provide high quality health care service for the patient which is associated with high mortality, complication, prolonged hospital stay, compromised quality of life and increase health care cost. Objective To determine medication related problems and its predictors in hospitalized heart failure patients at Jimma Medical Center, from May 30, 2019 to November 28, 2020 Methods A prospective interventional study was conducted among heart failure patients from May 30, 2019 to November 28, 2020 at Jimma Medical Center. Medication related problems were sorted based on Pharmaceutical care network Europe drug classification tool version 9.0. Patient’s specific data was collected using questionnaire. The data were coded, cleaned, and entered into Epidata version 4.6 and exported to SPSS version 25.0 for analysis .Binary Logistic regression was used to identify independent predictors of medication related problems occurrence. Variables having P-values < 0.05 were considered statistically significant Results A total of 384 heart failure patients were included in the study. The mean (SD) age was 49.06 ± 17.79. Two third of study participants had at least one medication related problem. A total of 483 MRPs were identified among 231(60.15%) patients. Treatment effectiveness related problem (55.48%) was the most common observed medication related problems. Alcoholism (AOR; 3.25, 95% CI (1.46–7.23), prolonged hospital stay [AOR = 3.67, 95%CI= (1.85–7.27)]; comorbidity [AOR = 2.88, 95%CI= (1.47–5.66)] and polypharmacy [AOR = 3.07, 95%CI= (1.57–5.99) were the independent predictors of medication related problems. Conclusion The prevalence of medication related problem was high among heart failure patients. Alcoholism, prolonged hospital stay, comorbidity and polypharmacy were the predictors of medication related problems. Hence, to overcome these problems, clinical pharmacists, physicians and other health care professionals have to work in collaboration.

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The Impact of Pharmacist-Based Services Across the Spectrum of Outpatient Heart Failure Therapy

Cited by 8 publications

References 75 publications

Drug-related problems and its predictors among hospitalized heart failure patients at Jimma Medical Center, South West Ethiopia: prospective interventional study

Drug-related problems and its predictors among hospitalized heart failure patients at Jimma Medical Center, South West Ethiopia: prospective interventional study

Utilizing Pharmacist-Led Telehealth Services in Ambulatory Patients with Heart Failure

Medication Related Problems and its predictors among heart failure patients at a tertiary care hospital in Ethiopia: A prospective interventional study

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