We present precise Sunyaev-Zeldovich (SZ) effect measurements in the direction of 62 nearby galaxy clusters (z < 0.5) detected at high signal-tonoise in the first Planck all-sky data set. The sample spans approximately a decade in total mass, 2 × 10 14 M < M 500 < 2 × 10 15 M , where M 500 is the mass corresponding to a total density contrast of 500. Combining these high quality Planck measurements with deep XMM-Newton X-ray data, we investigate the relations between D 2 A Y 500 , the integrated Compton parameter due to the SZ effect, and the X-ray-derived gas mass M g,500 , temperature T X , luminosity L X,500 , SZ signal analogue Y X,500 = M g,500 × T X , and total mass M 500 . After correction for the effect of selection bias on the scaling relations, we find results that are in excellent agreement with both X-ray predictions and recently-published ground-based data derived from smaller samples. The present data yield an exceptionally robust, high-quality local reference, and illustrate Planck's unique capabilities for all-sky statistical studies of galaxy clusters.