Although it sparked a lot of attention from the media and the public at the beginning of its release in 1998, even today's e-reader devices do not automatically beat the popularity of printed books. It is due to the inability of e-readers to provide responsive features, and there are still many book fans who are happy with their own experience of reading printed books. This study aims to analyze how perception and usability affect e-reader user satisfaction. The population in this study are followers of Autobase Twitter @literarybase. This study uses non-probability sampling with a purposive sampling technique. The sample chosen is people who have had the experience of reading a book using an e-reader device. Conducted The research with quantitative methods using data from 132 respondents through the distribution of questionnaires with a Likert scale as primary data. The test uses a data instrument, correlation coefficient, classical assumption test, and multiple linear regression test. The real test is done with SPSS software. The results showed that each variable, Perception (X1) and Usability (X2), had the same effect, either partially or jointly, on the Consumer Satisfaction variable (Y). The conclusion shows readers do not have problems with old stereotypes and perceptions about reading activities that e-reader devices cannot present. The absence of a distinctive fragrance, attractive cover, page-turning activity, and many other things closely related to printed books did not eliminate the pleasure of respondents when using the e-reader device. Readers also view usability on e-reader devices as good performance, both in terms of features, navigation, and device responsiveness.