The Impact of Different Types of Abuse on Depression

Radell, Milen L.; Hamza, Eid Abo; Daghustani, Wid H.; Perveen, Asma; Moustafa, Ahmed A.

doi:10.1155/2021/6654503

Cited by 41 publications

(28 citation statements)

References 135 publications

(183 reference statements)

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“…Although not statistically significant, psychological trauma showed a marginal association with the risk of developing MDD. This result was, in part, consistent with previous findings that psychological abuse was associated with depression ( 29 ). Some previous studies suggested that childhood emotional abuse and neglect were better predictors of adult depression than childhood sexual or physical trauma ( 10 , 13 ).…”

Section: Discussionsupporting

confidence: 92%

Bullying, Psychological, and Physical Trauma During Early Life Increase Risk of Major Depressive Disorder in Adulthood: A Nationwide Community Sample of Korean Adults

et al. 2022

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BackgroundThere is an association between early life traumas and the development of depression in adults. Few studies have used nationwide population-based samples to investigate whether the type of early life trauma differentially influences the risk of developing depression.MethodsMajor depressive disorder and early life trauma were assessed using the Korean version of the Composite International Diagnostic Interview (K-CIDI) for DSM-IV psychiatric disorder and a questionnaire for early life trauma in the Korean Epidemiological Catchment Area Study in 2016. A total of 4,652 participants were included in the final analysis. This study evaluated the effect of the type and frequency of reported early life trauma on the risk of developing MDD and the association between reported early life trauma and differential symptoms of MDD.ResultsIndividuals with reported early life trauma had a 3.7-fold increased risk of MDD. The risk of MDD was associated with bullying trauma (odds ratio (OR) = 1.847, p = 0.005) after adjusting for age, gender, marriage, job, and education years. The risk of MDD was increased as the types of reported early life traumas increased.ConclusionBullying trauma during early life represents a risk factor for MDD, especially in individuals exposed to multiple traumas in early life.

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Section: Discussionsupporting

confidence: 92%

Bullying, Psychological, and Physical Trauma During Early Life Increase Risk of Major Depressive Disorder in Adulthood: A Nationwide Community Sample of Korean Adults

et al. 2022

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“…The perinatal period is marked by changes in responsibilities, relationships, financial burdens, and sleep quality. However, these changes, as well as chronic stressors such as adverse experiences in childhood, previous physical, psychological, or sexual abuse and affective states such as negative body image, whilst increasing a woman's risk of PND, are also predictive of more general MDD (de Punder et al, 2018;Mullarkey et al, 2019;Radell et al, 2021).…”

mentioning

confidence: 99%

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non‐perinatal depression

Kiewa

Meltzer‐Brody

Milgrom

et al. 2022

Depression and Anxiety

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Background Distinctions between major depressive disorder (MDD) and perinatal depression (PND) reflect varying views of PND, from a unique etiological subtype of MDD to an MDD episode that happens to coincide with childbirth. This case–control study investigated genetic differences between PND and MDD outside the perinatal period (non‐perinatal depression or NPD). Methods We conducted a genome‐wide association study using PND cases (Edinburgh Postnatal Depression Scale score ≥ 13) from the Australian Genetics of Depression Study 2018 data (n = 3804) and screened controls (n = 6134). Results of gene‐set enrichment analysis were compared with those of women with non‐PND. For six psychiatric disorders/traits, genetic correlations with PND were evaluated, and logistic regression analysis reported polygenic score (PGS) association with both PND and NPD. Results Genes differentially expressed in ovarian tissue were significantly enriched (stdBeta = 0.07, p = 3.3e−04), but were not found to be associated with NPD. The genetic correlation between PND and MDD was 0.93 (SE = 0.07; p = 3.5e−38). Compared with controls, PGS for MDD are higher for PND cases (odds ratio [OR] = 1.8, confidence interval [CI] = [1.7–1.8], p = 9.5e−140) than for NPD cases (OR = 1.6, CI = [1.5–1.7], p = 1.2e−49). Highest risk is for those reporting both antenatal and postnatal depression, irrespective of prior MDD history. Conclusions PND has a high genetic overlap with MDD, but points of distinction focus on differential expression in ovarian tissue and higher MDD PGS, particularly for women experiencing both antenatal and postpartum PND.

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“…However, these actions can cause trauma and long-lasting harm to the child's mental health. This is an assault on an individual's autonomy that can degrade their self-image and confidence and eventually lead to clinical depression [10,20]. Probable mechanisms include overreactivity of the hypothalamic-pituitary-adrenal (HPA) axis which is also one of the most consistent psychoneuroendocrinological findings in MDD.…”

Section: Psychological Abusementioning

confidence: 99%

“…An ill-fostered caregiver-child attachment makes an individual perceive himself as unworthy, unlovable, and unreliable, which are prominent risk factors for MDD [8]. Certain cultures also endorse parents' power that tends to justify physical abuse and consider it acceptable, ultimately resulting in an adverse childhood experience [20].…”

Section: Physical Abusementioning

confidence: 99%

Childhood abuse and late life depression – Recent updates

Agarwal¹,

Sharma²,

Mandumpala³

2022

Indian J Child Health

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Childhood abuse is an important public health concern that can derail the developmental course of children. Psychological abuse, physical abuse and sexual abuse can have far-reaching impacts on children and influence the trajectories of mental health outcomes. They often co-occur and all maltreatment types carry a risk for depression in adulthood. Gaps in research methods pose challenges in extrapolating a generalized result that can influence the understanding of this probable link. Mechanisms correlating bio-psycho-social dimensions are relatively scarce. However, this review summarizes the recent updates in linking childhood abuse and major depressive disorder (MDD). Finally, targeted interventions and validated screening tools may be beneficial in the prevention of depression. This review highlights the importance of addressing childhood abuse and its sequelae in the development of depression.

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The Impact of Different Types of Abuse on Depression

Cited by 41 publications

References 135 publications

Bullying, Psychological, and Physical Trauma During Early Life Increase Risk of Major Depressive Disorder in Adulthood: A Nationwide Community Sample of Korean Adults

Bullying, Psychological, and Physical Trauma During Early Life Increase Risk of Major Depressive Disorder in Adulthood: A Nationwide Community Sample of Korean Adults

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non‐perinatal depression

Childhood abuse and late life depression – Recent updates

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