2017
DOI: 10.1016/j.toxlet.2017.04.006
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The immunotoxicological pattern of subchronic and chronic benzene exposure in rats

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Cited by 23 publications
(10 citation statements)
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“…At PND 50, male offspring were scarified and the relative weight of spleen and thymus was calculated in relation to body weight [ [40] , [41] ].…”
Section: Methodsmentioning
confidence: 99%
“…At PND 50, male offspring were scarified and the relative weight of spleen and thymus was calculated in relation to body weight [ [40] , [41] ].…”
Section: Methodsmentioning
confidence: 99%
“…The cells were collected and stained with PE-CD3, FITC-CD4, and Percp/cy5.5-CD8, respectively. The percentage of CD3 + T, CD4 + T, and CD8 + T cells was analyzed by flow cytometry. , The values are presented as means ± SD ( n = 3). * P < 0.05 and ** P < 0.01 versus blank treatment.…”
Section: Methodsmentioning
confidence: 99%
“…The percentage of CD3 + T, CD4 + T, and CD8 + T cells was analyzed by flow cytometry. 41,42 The values are presented as means ± SD (n = 3). *P < 0.05 and **P < 0.01 versus blank treatment.…”
Section: ■ Experimental Sectionmentioning
confidence: 99%
“…Based on epidemiological studies, human exposed to high levels of benzene show an increased risk to develop several acute and chronic diseases, such as acute myeloid leukemia, acute and chronic lymphocytic leukemia, non-Hodgkin lymphoma, multiple myeloma and aplastic anaemia [2] . Moreover, exposure to low doses of benzene has been linked to increased incidence of myelodisplastic syndrome and decreased resistance to infection [3] , which may be explained by its immunotoxic activity targeting mainly T-cells [4] .…”
Section: Introductionmentioning
confidence: 99%