The Immunological Relationships of Strains of Contagious Pustular Dermatitis Virus

Horgan, E. S.; Haseeb, M. A.

doi:10.1016/s0368-1742(47)80001-3

Cited by 10 publications

(5 citation statements)

References 2 publications

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“…The study revealed a more or less close serological cross-reactivity of all strains, thus confirming the conclusions drawn by others [1,[3][4][5]8,9]. A tentative grouping into two antigenic groups is questioned by the facts that a low-passage Orf virus (D 1701/8) and its high-passage progeny (D 1701 /137) fall into each of the two groups and that there is no correlation between these groups and the clinical origin of the virus strains.…”

Section: Discussionsupporting

confidence: 80%

“…Close immunological and bio logical resemblance has been reported between isolates from bovine cases of stomatitis papu losa (SP) and pseudocowpox virus infections and from the corresponding human disease, milker's nodules [1,2]. The same holds true for ovine and human isolates of dermatitis pustulosa or Orf virus infection [3][4][5]. Based on such findings, Nagington [6] proposed a classifica tion according to case history into bovine or ovine strains including the corresponding hu man isolates.…”

mentioning

confidence: 74%

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Genetic and Antigenic Heterogeneity of Different Parapoxvirus Strains

Wittek

Herlyn

Schümperli³

et al. 1980

Intervirology

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Six stomatitis papulosa and three Orf virus strains were compared by serology and by DNA restriction analysis. A neutralization kinetic study revealed extensive serological cross-reactivity between all strains, but did not allow their classification. Restriction analysis of viral DNAs revealed two distinct groups among the stomatitis papulosa strains while the Orf virus strains formed a third, more heterogeneous group. The large heterogeneity of restriction patterns of parapoxvirus DNAs as compared to those of orthopoxviruses is discussed.

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Section: Discussionsupporting

confidence: 80%

mentioning

confidence: 74%

Genetic and Antigenic Heterogeneity of Different Parapoxvirus Strains

Wittek

Herlyn

Schümperli³

et al. 1980

Intervirology

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“…Clinical signs in naïve sheep and goats generally begin as localized erythema and development of pustules and vesicles at the site of infection. These results support findings of other studies, 3,5,8,[19][20][21] which suggest that strains of orf virus antigenically distinct from those in the goat-derived CE vaccine are a cause of disease outbreaks in sheep and goats. Lesions heal by 4 to 8 weeks after infection.…”

Section: Discussionsupporting

confidence: 91%

Evaluation of homologous and heterologous protection induced by a virulent field strain of orf virus and an orf vaccine in goats

Musser¹,

Waldron²,

Taylor³

2012

ajvr

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“…These differences can be attributed to antigenic and virulence differences of contagious ecthyma strains. 13,15,18,19 Scab formation following vaccination is desirable because it is an indirect indication of successful vaccination, whereas no scab formation at the site of challenge is an indirect assessment of the protective immunity derived from the vaccination. Because 47CE had the largest vaccine-to-challenge scab formation ratio and was substantially different from the strains with lower ratios, it was chosen for development into the vaccine to be examined for efficacy; however, use of viral strain 131CE may have resulted in similar findings.…”

Section: Discussionmentioning

confidence: 99%