The iBreastExam versus clinical breast examination for breast evaluation in high risk and symptomatic Nigerian women: a prospective study

Mango, Victoria L.; Olasehinde, Olalekan; Omisore, Adeleye Dorcas; Wuraola, Funmilola; Famurewa, O.; Sevilimedu, Varadan; Knapp, Gregory C; Steinberg, Evan A.; Akinmaye, Promise R; Adewoyin, Boluwatife D; Romanoff, Anya; Castle, Philip E.; Alatise, Olusegun Isaac; Kingham, T. Peter

doi:10.1016/s2214-109x(22)00030-4

Cited by 18 publications

(22 citation statements)

References 24 publications

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“…In a study done by Mango D et al, I Breast Exam and clinical breast examination when used together, reported sensitivity for suspicious masses would improve, but specificity would decrease. They also found better sensitivity and specificity for masses which are suspicious in non dense breasts as compared to dense breasts [15]. Xu and colleagues reported results of breast-i exam were not influenced by breast density [16].…”

Section: Discussionmentioning

confidence: 97%

Breast-I AS A screening tool in detecting early breast lesions in women-An experimental study in tertiary care centre Chennai

Selvaraj

Kubendran

Pattabi

2022

ijhs

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Background: India is facing challenging situation because the incidence of breast cancer has increased by 14% and the mortality rate has increased by 11.1%. Breast- i is a new tool for effective breast cancer screening, especially for detecting both non-palpable and very small lesions often missed by Clinical Breast Examination (CBE). This device is expected to help in detecting tiny breast lesions in the outpatient clinic itself, helping in reducing morbidity and mortality associated with late diagnosis of carcinoma breast. Objectives: To analyze diagnostic accuracy of Breast-i and to study the prevalence of Breast Cancer in the study population. Materials and Methods: The experimental study was conducted at Sree Balaji Medical College and Hospital, Chennai over eighteen months with sixty female patients using Breast-i for early diagnosis of Breast lesions. Detailed history was taken and CBE was done. Later, patients were screened with Breast-i and further evaluation was done if abnormalities were detected with Breast-i. The findings obtained from Breast-i were compared with FNAC and Trucut Biopsy finding. The obtained data were processed with MedCalc Software Version 19.0.

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Section: Discussionmentioning

confidence: 97%

Breast-I AS A screening tool in detecting early breast lesions in women-An experimental study in tertiary care centre Chennai

Selvaraj

Kubendran

Pattabi

2022

ijhs

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“…PEF has been successfully tested in vivo with better sensitivity than mammography and has been shown to be able to detect breast cancers in women with dense breasts that were undetectable via mammography (Xu et al 2016 ). The UELS has licensed the technology and received FDA approval with the PEF breast cancer detector marketed under the trade name intelligent Breast Exam (iBE®) (Mango et al 2022 ).…”

Section: Piezoelectric Biomaterialsmentioning

confidence: 99%

Bio-piezoelectricity: fundamentals and applications in tissue engineering and regenerative medicine

Kamel

2022

Biophys Rev

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In recent years, smart materials have piqued the interest of scientists and physicians in the biomedical community owing to their ability to modify their properties in response to an external stimulation or changes in their surroundings. Biocompatible piezoelectric materials are an interesting group of smart materials due to their ability to produce electrical charges without an external power source. Electric signals produced by piezoelectric scaffolds can renew and regenerate tissues through special pathways like that found in the extracellular matrix. This review summarizes the piezoelectric phenomenon, piezoelectric effects generated within biological tissues, piezoelectric biomaterials, and their applications in tissue engineering and their use as biosensors.

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“…The study generated essential data that might be the basis for further research on breast cancer diagnosis, downstaging, and screening in LMICs. Mango and colleagues 6 showed that the iBreastExam performed well, showing superior sensitivity over clinical breast examination for any breast lesion (63%, 95% CI 57-69 vs 31%, 25-37; p<0•0001) and similar sensitivity to clinical breast examination for suspicious lesions (86%, 70-95 vs 83%, 67-94; p=0•65). The findings show that the iBreastExam has potential to bridge some deficiencies and gaps in the decision-making process, especially for community health-care providers.…”

Section: Breast Cancer Screening: Can the Ibreastexam Bridge The Gap?mentioning

confidence: 99%

Breast cancer screening: can the iBreastExam bridge the gap?

Olaogun

Agodirin

2022

The Lancet Global Health

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The iBreastExam versus clinical breast examination for breast evaluation in high risk and symptomatic Nigerian women: a prospective study

Cited by 18 publications

References 24 publications

Breast-I AS A screening tool in detecting early breast lesions in women-An experimental study in tertiary care centre Chennai

Breast-I AS A screening tool in detecting early breast lesions in women-An experimental study in tertiary care centre Chennai

Bio-piezoelectricity: fundamentals and applications in tissue engineering and regenerative medicine

Breast cancer screening: can the iBreastExam bridge the gap?

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