The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Application of TNM Staging Rules to Lung Cancer Presenting as Multiple Nodules with Ground Glass or Lepidic Features or a Pneumonic Type of Involvement in the Forthcoming Eighth Edition of the TNM Classification

Abstract

For multifocal ground glass/lepidic tumors, we propose that the T category be determined by the highest T lesion, with either the number of tumors or m in parentheses to denote the multifocal nature, and that a single N and M category be used for all the lesions collectively-for example, T1a(3)N0M0 or T1b(m)N0M0. For diffuse pneumonic-type lung cancer we propose that the T category be designated by size (or T3) if in one lobe, as T4 if involving an ipsilateral different lobe, or as M1a if contralateral and that a single N and M category be used for all pulmonary areas of involvement.

The IASLC Lung Cancer Staging Project: A Renewed Call to Participation

“…22 From this second, international database, the IASLC SPFC developed recommendations toward the eighth edition of the TNM staging system. These recommendations were published in 2015, 2016, and 2017 [23][24][25][26][27][28][29][30][31][32][33] and were once again accepted by the UICC 34 and AJCC 35 in 2017 (with AJCC implementation effective in 2018) and included in the second edition of the IASLC Staging Manual in Thoracic Oncology and the IASLC Staging Handbook in Thoracic Oncology.…”

Epidemiology, risk factors, symptomatology, TNM classification of Non Small Cell Lung Cancer. An overview while waiting the 8th TNM classification

“…However, in this area a further classification has also been proposed (N1a, N1b, N2a, N2b, and N3) (63). In addition, Detterbeck FC et al proposed an inclusion of LC types that are presented as multiple pulmonary sites or multiple nodules with ground glass or lepidic features or LC with a pneumonic type of involvement in the 8 th TNM classification (64,65). The health professionals who are engaged with the therapy and diagnosis of NSCLC and generally LC anticipate the upcoming TNM classification as it is expected to change the therapeutic approach of one to six patients (57,58).…”

The eighth staging system of non-small cell lung cancer and its practical implications

“…Pnömonik tip adenokarsinom için tanımlanan bu şema adenokarsinomun milier formu için de kullanılabilir. [9][10][11][12] Tümör invazyonu: Herhangi bir boyuttaki tümörün lokal yayımının değerlendirilmesinde rutin olarak kullanılan standart inceleme toraks BT'dir. İncelemenin kontrastlı yapılması invazyonun daha iyi değerlendirilmesini sağlar.…”